Bio Med - Day 4a Flashcards
Inflammation of the stomach lining (either Acute or Chronic)
Gastritis
Acute Gastritis, which rapidly develops, can be due to what
NSAID use
Alcohol
H. pylori infection
Stress from severe illness (e.g., burns, CNS injury, etc.)
Type A Chronic Gastritis occurs in the _______, and is due to autoantibodies in the parietal cells. It also accounts for ________% of Chronic Gastritis
Fundus
10
What type of anemia is caused by Type A Chronic Gastritis, and what other conditions is it associated with
Pernicious Anemia
Thyroiditis
Gastric Adenocarcinoma
Type B Chronic Gastritis (accounts for 90% of Chronic Gatritis), occurs in the _______, and is most likely due to ________ use, or _________ infection
Antrum
NSAID
H. pylori
What is the Pernicious Anemia due to in relationship to Gastritis
Lack of Intrinsic factor which is required for Vit B12 absorption
Histamine 1 Drugs, and what they do
H1 receptor blockers
Diphenhydramine Mepyramine Maleate Promethazine Hydrochloride Pheniramine Maleate Antazoline
***These drugs treat allergic reactions
Histamine 1 Drugs, and what they do
H1 receptor blockers
Diphenhydramine (Benadryl, Nytol, Dramamine)
Mepyramine Maleate
Promethazine (Phenergan, Phenadoz, Promethean)
Hydrochloride
Pheniramine Maleate (Avil)
Antazoline
***These drugs treat allergic reactions
Histamine 2 Drugs, and what they do
H2 receptor blockers
Cimetidine (Tagamet) Burimamide Metiamide Ranitidine (Zantac) Nazitinidine (Axid) Famotinidine (Pepcid)
***To reduce Gastric Acid and Release; H2 receptors are in the stomach
What is PUD, Peptic Ulcer Disease
Damage to the Gastric to Duodenal mucosa; caused by impaired mucosal defense, or increased acidic acid contents
What is the main cause of PUD
H. Pylori
Other causes of PUD
Corticosteroid
NSAID
Alcohol
Tabacco
With Duodenal Ulcers _____ is the causative factor in 90% of cases.
Pain ________ with meals
H. pylori
Decrease
With Gastric Ulcers _____ is the causative factor in 70% of cases.
Pain ________ with meals
H. pylori
Greater
How are PUD diagnosed
Upper endoscopy with biopsy
H. pylori test via Urea Breath testing
Complications of PUD
hint “HOPI”
Hemorrhage
Obstruction
Perforation - (can lead to Peritonitis)
Intractable Pain