B2.1 Membranes and membrane transport SL Flashcards
Composition of biological membranes?
Lipids, proteins, carbohydrates.
Structure of a phospholipid?
Glycerol, hydrophilic phosphate head, hydrophobic fatty acid tails.
Amphipathic nature of phospholipids?
Hydrophobic tails, hydrophilic heads.
Phospholipid arrangement in water?
Bilayer: hydrophobic tails inward, hydrophilic heads outward
Role of cholesterol in lipid bilayers?
Modulates fluidity and stability.
What determines lipid bilayer’s selective permeability?
Hydrophobic core blocks ions/polar molecules, allows non-polar molecules.
Simple diffusion?
Passive movement down concentration gradient.
Integral vs. peripheral proteins?
Integral: embedded in bilayer; Peripheral: on surface.
Function of aquaporins?
Rapid water transport across membranes.
Facilitated diffusion?
Passive transport via protein channels/carriers.
Channel vs. carrier proteins?
Channel: pores; Carrier: bind and transport molecules.
Active transport?
Movement against concentration gradient, requires energy.
Glycoproteins and glycolipids function?
Cell recognition, signaling, adhesion.
Fluid mosaic model?
Dynamic mix of moving phospholipids and proteins.
Role of the glycocalyx?
Cell protection, adhesion, recognition.