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Pharma > Asthma > Flashcards

Asthma Flashcards

1
Q

Long Acting Beta 2 Agonist

A 
Salmeterol
Formoterol
Cleneterol
Bambuterol
Arformoterol
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2
Q

Salmeterol is not used as a monotherapy. What drug is used (potentiation)?

A

Inhaled corticosteroids

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3
Q

Drug of choice for acute asthma attacks

A

Salbutamol/ Albuterol
Terbutaline
Pirbuterol
Procaterol

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4
Q

Can cause tolerance/tachyphylaxis
Tachycardia
Tremors
May precipitate arrhythmias in patients with concurrent COPD and heart disease

A

Beta 2 agonists

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5
Q

Muscarinic receptor antagonist that is more effective and less toxic in patients with COPD

A

Ipratropium

Tiotropium

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6
Q

Methylxanthine derivative that inhibits adenosine through phosphodiesterase 3 which causes bronchodilation.

A

Theophylline
Aminophylline
Pentoxifylline

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7
Q

Methylxanthine derivative that is used for nocturnal asthma prophylaxis and has a narrow therapeutic window

A

Theophylline

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8
Q

Methylxanthine derivative used for intermittent claudication

A

Pentoxifylline

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9
Q

Antidote for theophylline overdosage

A

Beta blockers

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10
Q

Mast cell stabilizer that prefers degranulation and release of histamine for asthma prophylaxis

No bronchodilator action

A

Cromolyn
Nedocromil
Lodoxamide

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11
Q

Corticosteroid that inhibits phospholipase A2 that reduces expression of COX

Drug of choice for asthma prophylaxis

A 
Fluticasone
Budesonide
Beclomethasone
Mometasone
Ciclesonide
Triamcinolone
Flunisonide
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12
Q

Drug used for asthma prophylaxis that can cause oropharyngeal candidiasis

A

Fluticasone

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13
Q

Used in the treatment of severe refractory asthma

A

IV hydrocortisone

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14
Q

Corticosteroid with lowest systemic steroid toxicity

A

Ciclesonide

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15
Q

Leukotriene synthesis inhibitors that inhibits 5-lipooxygenase used for asthma prophylaxis

A

Zileuton

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16
Q

Leukotriene receptor antagonist for C4,D4,E4 which prevents airway inflammation and bronchoconstriction

A

Montelukast
Pranlukast
Zafirlukast

17
Q

Anti-IgE antibody that binds IgE antibodies on mast cells and reduces reaction to inhaled antigen

Refractory asthma not responsive to all other drugs

A

Omalizumab

Pharma (15 decks)

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