AP 22 Nov Quizlet Flashcards
State where kidneys retain water to maintain osmolarity.
Water Conservation
Concentration of solutes in a solution, measured in mOsm.
Osmolarity
Nephron segment where osmolarity matches plasma (300 mOsm).
Proximal Tubule
Nephron segment that dilutes urine to 100 mOsm.
Thick Ascending Limb
Part of nephron that reduces tubular fluid osmolarity.
Diluting Segment
Hormone that increases water reabsorption in kidneys.
ADH
Concentration of solutes in kidney interstitial fluid.
Interstitial Osmolarity
Treatment that increases urine output and reduces fluid volume.
Diuretic Therapy
Fluid outside cells, important for fluid balance.
Extracellular Fluid
Hormone that regulates blood pressure and fluid balance.
Angiotensin II
Narrowing of renal artery affecting blood flow and pressure.
Renal Artery Stenosis
Test to estimate glomerular filtration rate (GFR).
Creatinine Clearance
Reduction in functional nephron units affecting kidney function.
Nephron Loss
Compensatory increase in size of remaining nephrons.
Physiologic Hypertrophy
Rate at which blood is filtered by the kidneys.
Filtration Rate
Limiting sodium intake to reduce kidney workload.
Sodium Restriction
Limiting potassium intake to maintain balance in kidneys.
Potassium Restriction
Dietary protein affecting kidney function and workload.
Protein Intake
Different areas in the body where fluids are distributed.
Body Fluid Compartments
Saline solution with lower osmolarity than blood plasma.
Hypotonic Saline
Saline solution with higher osmolarity than blood plasma.
Hypertonic Saline
Movement of fluids between body compartments.
Fluid Distribution
High blood pressure influenced by salt intake.
Salt-Sensitive Hypertension
Surgical removal of one kidney affecting overall function.
Unilateral Nephrectomy
Diuretics that help retain potassium in the body.
Potassium-Sparing Diuretics
Diuretics that increase potassium excretion in urine.
Potassium-Wasting Diuretics
Homeostasis of fluids and electrolytes in the body.
Fluid and Electrolyte Balance
Mechanisms controlling blood pressure via renal function.
Blood Pressure Regulation
Enlargement of remaining nephrons after loss.
Nephron Hypertrophy
Glomerular Filtration Rate per nephron increases.
Single Nephron GFR
Abnormal enlargement due to increased nephron workload.
Pathologic Hypertrophy
Progressive decline in kidney function over time.
Nephron Loss Impact
Kidneys fail to perform normal functions.
Renal Failure
Limit sodium and potassium to ease kidney burden.
Dietary Restrictions
Two-thirds of total body water volume.
Intracellular Fluid
Isotonic solution used to maintain osmolarity.
0.9% Saline
Occurs from extracellular to intracellular fluid.
Water Movement
Increases as water is reabsorbed in nephron.
Tubular Fluid Concentration
Nephron cells that reabsorb water and salts.
Principal Cells
Final nephron segment for water reabsorption.
Collecting Duct
Osmolarity in kidney tissue surrounding nephrons.
Renal Interstitial Concentration
Concentration of solutes in urine.
Urine Osmolarity
Homeostasis of body fluids and electrolytes.
Fluid Balance
Kidneys manage levels of ions in body.
Electrolyte Regulation
Intracellular and extracellular spaces in the body.
Fluid Compartments
Equilibrium of solute concentration across compartments.
Osmolarity Balance
Process of reclaiming substances from tubular fluid.
Reabsorption Mechanism
Fluid surrounding renal tubules, influences osmolarity.
Renal Interstitium
Proteins facilitating water reabsorption in kidneys.
Water Channels
Movement of water across membranes due to concentration gradients.
Osmosis
Fluid within nephron, undergoes filtration and reabsorption.
Tubular Fluid
Waste product filtered by kidneys, concentration varies with water reabsorption.
Creatinine
Nephron section concentrating urine through countercurrent multiplication.
Loop of Henle
Transporter reabsorbing Na+, K+, and Cl- in nephron.
Sodium-Potassium-Chloride Transporter
Para-aminohippuric acid, used to measure renal plasma flow.
PAH
Medications increasing urine production, often for hypertension.
Diuretics
Process where urea is reabsorbed, influenced by ADH.
Urea Reabsorption
Condition of reduced osmolarity, often due to excess water.
Hypoosmolarity
Process of reclaiming ions from tubular fluid back into blood.
Electrolyte Reabsorption
Difference in solute concentration across a membrane.
Concentration Gradient
Process of eliminating excess fluid from the body.
Fluid Excretion
Condition often treated with diuretics to reduce fluid volume.
High Blood Pressure
Network of nephron segments involved in urine formation.
Tubular System
Inner kidney region, crucial for urine concentration.
Renal Medulla
Kidney state focused on retaining water during dehydration.
Water Conservation Mode
Variations in solute concentration throughout nephron segments.
Osmolarity Changes
Distinct body areas where fluids are contained.
Fluid Compartment
Mechanism enhancing urine concentration in the Loop of Henle.
Countercurrent Multiplication
Medication that promotes fluid excretion via urine.
Diuretic
Increased urine production due to fluid loss.
Diuresis
Fluid outside cells, includes plasma and interstitial fluid.
Extracellular Fluid (ECF)
One-fifth of the extracellular fluid volume.
Plasma Portion
Fluid between cells, makes up four-fifths of ECF.
Interstitial Fluid
Removal of sodium from the body via urine.
Sodium Excretion
Maintaining proper levels of ions in body fluids.
Electrolyte Balance
Force exerted by circulating blood on vessel walls.
Blood Pressure
Resistance blood vessels offer against blood flow.
Vascular Resistance
Volume of urine produced by kidneys.
Urine Output
Regulates fluid balance and electrolyte levels.
Kidney Function
Decreasing total body fluid to lower blood pressure.
Fluid Volume Reduction
Sustained treatment to manage chronic conditions.
Long-term Therapy
Hormone that promotes water reabsorption in kidneys.
ADH (Antidiuretic Hormone)
Diet rich in sodium, often leading to increased thirst.
High Sodium Diet
System responsible for blood circulation in the body.
Cardiovascular System
First-time administration of a medication.
Initial Drug Exposure
Fluid lost through urination, affecting body fluid levels.
Urinary Loss
Amount of sodium consumed through diet.
Sodium Intake
Excess fluid accumulation in the body.
Fluid Retention
Modifications made to medication dosage or type.
Therapeutic Adjustments
Kidneys’ role in maintaining fluid and electrolyte homeostasis.
Kidney Regulation