AP 15 Nov Quizlet Flashcards
Blood flow through the kidneys for filtration.
Renal Plasma Flow
Rate of blood filtration in the glomeruli.
Glomerular Filtration Rate (GFR)
Cells sensing sodium and chloride to adjust GFR.
Macula Densa
Hormone constricting efferent arterioles to regulate GFR.
Angiotensin II
Increased filtration risk due to high solute levels.
Hyperfiltration
Site for glucose and amino acid reabsorption.
Proximal Tubule
True renal plasma flow accounting for pH changes.
Effective Renal Plasma Flow
Measurement of kidney’s ability to clear substances.
Clearance Rate
Standard for measuring renal clearance and function.
Inulin Clearance
Indicator of renal function based on creatinine levels.
Creatinine Clearance
Pressure determining fluid movement into Bowman’s capsule.
Net Filtration Pressure
Measure of the permeability of glomerular capillaries.
Filtration Coefficient
Transporters facilitating glucose reabsorption in kidneys.
Sodium-Glucose Cotransporters (SGLT)
Transporters aiding amino acid reabsorption in kidneys.
Sodium-Amino Acid Cotransporters (SMAT)
Mechanism enhancing concentration of urine in kidneys.
Counter Current Multiplier
Process of reclaiming water and solutes in kidneys.
Fluid Reabsorption
Amount of urine produced by the kidneys.
Urine Volume
Rapid fluid movement affecting solute reabsorption.
Ascending Flow Rates
High blood pressure impacting renal function and GFR.
Hypertension
Condition reducing GFR and urine output.
Low Blood Pressure
Space between renal tubules important for solute exchange.
Renal Interstitium
Study of factors influencing glucose reabsorption rates.
Glucose Transport Kinetics
Total amount of substance filtered by kidneys.
Filtered Load
Blood glucose level where glucose appears in urine.
Threshold Point
Condition leading to hyperfiltration and kidney damage.
Chronic High Glucose Levels
Process of eliminating excess fluid from the body.
Fluid Excretion
Potential harm from prolonged abnormal blood pressure.
Kidney Damage Risks
Rapid upward blood flow reduces protein reabsorption.
Ascending Flow
Volume of plasma cleared of a substance.
Clearance
Substance heavily cleared by the kidneys.
PAH
Used to measure kidney function, requires complex measurements.
Inulin
Commonly used to assess renal function trends.
Creatinine
Blood vessel carrying blood away from glomerulus.
Efferent Arteriole
Blood vessel supplying blood to glomerulus.
Afferent Arteriole
Kidney’s ability to maintain blood flow despite pressure changes.
Autoregulation
Site of filtration in the kidney.
Glomerular Capillaries
Glomerular filtration rate, normal is 125 mL/min.
GFR
Volume of blood supplied to the kidneys.
Renal Blood Flow
Process of returning substances to the blood.
Reabsorption
Calculated using net filtration pressure and coefficient.
Filtration Estimate
Difference in solute concentration across a membrane.
Concentration Gradient
Excess fluid leading to potential health issues.
Fluid Overload
Mechanism to control blood pressure in kidneys.
Pressure Regulation
Maximum volume bladder can hold before discomfort.
Bladder Capacity
Elevated filtration leading to increased urine output.
Filtration Rate Increase
Short-term increase during physical activity.
Temporary Blood Pressure Rise
Long-term high blood pressure causing renal damage.
Sustained Hypertension
Excessive fluid loss due to uncontrolled filtration.
Fluid Dumping
Evaluating kidney performance through various metrics.
Renal Function Assessment
Normal pressure is 60 mmHg, can rise with hypertension.
Pressure at Glomerulus
Force exerted by circulating blood on vessel walls.
Blood Pressure
Pressure in the renal artery supplying kidneys.
Renal Arterial Pressure
Pressure within glomerular capillaries affecting filtration.
Glomerular Capillary Pressure
Artery supplying blood to the glomerulus.
Afferent Arterial
Artery draining blood from the glomerulus.
Efferent Arterial
Process of removing waste from blood in kidneys.
Filtration
Volume of urine produced by the kidneys.
Urine Output
Condition causing potential kidney damage over time.
High Blood Pressure
Network of capillaries involved in filtration.
Capillary Bed
Cells in glomerulus maintaining filtration barrier.
Podocytes
Small openings in capillaries allowing filtration.
Fenestrations
Kidney’s ability to maintain stable GFR despite pressure changes.
Auto-regulation
Damage caused by reactive oxygen species in tissues.
Oxidative Stress
Opposition to blood flow in blood vessels.
Vascular Resistance
Structure in kidneys where reabsorption occurs.
Tubule
Reduced ability to dilate, impacting blood flow.
Stiff Blood Vessels
Long-term impairment of kidney function due to pressure.
Chronic Kidney Damage
Speed at which blood is filtered in kidneys.
Filtration Rate
Kidneys’ process of retaining useful substances.
Selective Reabsorption
Medication relaxing afferent arterioles to reduce pressure.
Calcium Channel Blocker
Medication primarily affecting afferent arterial dilation.
Beta Blocker
Prolonged high blood pressure leading to kidney damage.
Long-term Hypertension
Kidneys’ ability to conserve fluid during low pressure.
Blood Volume Retention
Drug that constricts both afferent and efferent arterioles.
Phenylar
Sensor at macula densa measuring filtration rate.
Filtration Speedometer