AP 13 Nov Quizlet Flashcards
Volume of plasma cleared of a substance per time.
Renal Clearance
Kidneys manage long-term blood pressure levels.
Blood Pressure Regulation
Kidneys regulate pH by managing bicarbonate levels.
Acid-Base Balance
Kidneys release erythropoietin to increase red blood cells.
Hematocrit Regulation
Kidneys manage sodium and calcium levels.
Electrolyte Balance
Kidneys produce bicarbonate to neutralize excess protons.
Bicarbonate Production
Hormone released by kidneys in response to low oxygen.
Erythropoietin (EPO)
Kidneys convert vitamin D for calcium management.
Vitamin D Activation
Kidneys reabsorb glucose unless levels are excessively high.
Blood Glucose Regulation
Normal GFR is approximately 125 mL/min.
Glomerular Filtration Rate (GFR)
Gold standard for accurately measuring GFR.
Inulin
Commonly used to estimate GFR but can overestimate.
Creatinine
Includes cortical and medullary nephrons.
Nephron Structure
Facilitate reabsorption and secretion in nephrons.
Peritubular Capillaries
First segment of nephron for reabsorption.
Proximal Tubule
Part of nephron involved in urine concentration.
Loop of Henle
Segment of nephron for further reabsorption.
Distal Convoluted Tubule
Final segment of nephron for urine concentration.
Collecting Ducts
Kidneys concentrate urine by reabsorbing water.
Urinary Concentration
Kidneys clear drugs activated or deactivated by liver.
Drug Clearance
Kidneys eliminate nitrogenous waste like urea.
Metabolic Waste Management
Rate of urine production measured in mL/min.
Urinary Flow Rate
Amount of substance secreted into urine.
Secretion Rate
Amount of substance reabsorbed back into blood.
Reabsorption Rate
Volume of plasma flowing through kidneys per time.
Renal Plasma Flow
Mineral deposits that can block urine flow.
Kidney Stones
Controls bladder and bowel emptying.
Pudendal Nerve
Surrounds urethra; can cause urinary issues.
Prostate Gland
Hormone released by kidneys to stimulate red blood cell production.
EPO (Erythropoietin)
Condition of low oxygen levels in kidney tissue.
Hypoxic
Process of absorbing substances back into the bloodstream.
Reabsorption
Kidney’s management of sodium levels in the body.
Sodium Regulation
Kidney’s ability to reabsorb calcium from filtered fluid.
Calcium Reabsorption
Threshold beyond which glucose cannot be reabsorbed.
Transport Maximum
Presence of glucose in urine due to high blood sugar.
Glucosuria
Liver enzymes involved in drug metabolism.
Cytochrome P450
Toxic compounds like urea eliminated by kidneys.
Nitrogenous Waste
Kidney’s role in regulating blood osmolarity.
Osmolarity Management
Kidney’s selective absorption of water from filtrate.
Water Reabsorption
Brain sensors that regulate kidney water reabsorption.
Osmoreceptors
Rate at which blood is filtered by kidneys.
GFR (Glomerular Filtration Rate)
Kidney’s ability to maintain stable GFR levels.
Autoregulation of GFR
Major arteries supplying blood to the kidney.
Segmental Arteries
Arteries that branch from segmental arteries in kidneys.
Interlobar Arteries
Arteries that arch over the renal pyramids.
Arcuate Arteries
Small arteries branching from arcuate arteries.
Interlobular Arteries
Tissue space within the kidney surrounding nephrons.
Renal Interstitium
Physiological reaction to increase red blood cell count.
Colitis Response
Kidney’s function in maintaining homeostasis over time.
Long-term Regulator
Kidney’s process of reclaiming electrolytes from filtrate.
Electrolyte Reabsorption
Condition of elevated sodium levels in the blood.
Hypernatremia
Substances produced by metabolism, excreted by kidneys.
Metabolic Waste Products
Arterioles supplying blood to glomeruli.
Afferent Arterioles
Arterioles draining blood from glomeruli.
Efferent Arterioles
Veins formed from peritubular capillaries.
Interlobular Veins
Veins formed from interlobular veins.
Arcuate Veins
Veins formed from arcuate veins.
Interlobar Veins
Veins formed from interlobar veins.
Segmental Veins
Final veins draining blood from kidneys.
Renal Veins
Basic functional unit of the kidney.
Nephron
Nephrons located in the outer cortex.
Cortical Nephrons
Nephrons extending deep into the medulla.
Medullary Nephrons
Special capillaries in deep medullary nephrons.
Basorecta Capillaries
Capillaries forming the glomerulus.
Glomerular Capillaries
Network responsible for reabsorption and secretion.
Tubular System
Process of adding substances to urine.
Secretion
Speed of blood flow in capillaries.
Fluid Velocity
Capillaries moving deeper into the medulla.
Descending Capillaries
Capillaries returning towards the cortex.
Ascending Capillaries
Each kidney contains approximately 1 million nephrons.
Nephron Count
Minimal loss until around age 40.
Nephron Loss
90-95% of nephrons are cortical.
Cortical Nephron Percentage
5-10% of nephrons are medullary.
Medullary Nephron Percentage
Interconnected capillaries facilitating blood flow.
Capillary Network
Difference in solute concentration across regions.
Concentration Gradient
Nephrons with limited blood supply, sensitive to hypotension.
Deep Medullary Nephrons
Insufficient blood flow causing tissue damage.
Ischemia
Descending vaso recta, a type of capillary.
DVR
Capillaries supplying blood to kidney’s inner regions.
Ascending Vaso Recta
Artery supplying blood to the kidneys.
Renal Artery