Antiprotozoan and Antihelminthic Agents

Question 1

Chemoprophylaxis for malaria?

Answer 1

Chloroquine

Question 2

Tx of Plasmodium falciparum and erythrocytic form of P. vivax and P. ovale?

Answer 2

Chloroquine

Question 3

Tx of drug-resistant P. falciparum?

Answer 3

Quinine and mefloquine

Question 4

Tx for Babesia microti?

Answer 4

Quinine

Question 5

Tx for hepatic forms of P. vivax and P. ovale?

Answer 5

Primaquine

Question 6

Prophylaxis for Pneumocystis carinii pneumonia?

Answer 6

Pentamidine

Question 7

Tx for T. cruzi infection?

Answer 7

Nifurtimox

Question 8

Tx for early T. brucei infection?

Answer 8

Suramin

Question 9

Tx for late T. brucei infection?

Answer 9

Melarsoprol

Question 10

Tx of leishmaniasis?

Answer 10

Sodium stibogluconate

Question 11

Tx for river blindness (Onchocerciasis)?

Answer 11

Ivermectin

Question 12

Tx for whipworm, hookworm, roundworm, pinworm?

Answer 12

-bendazole

Question 13

Tx for hookworm, roundworm, and pinworm when -bendazoles do not work?

Answer 13

Pyrantel pamoate

Question 14

Tx for schistosomiasis, neurocysticercosis, hydatid dz, and tapeworms?

Answer 14

Praziquantel

Question 15

Inhibits heme metabolism?

Answer 15

Chloroquine

Question 16

Causes GI upset, pruritis, visual changes, and ECG changes?

Answer 16

Chloroquine

Question 17

Causes hemolytic anemia in G6PD deficient pts?

Answer 17

Primaquine

Question 18

Activates GABA receptors leading to worm paralysis and death?

Answer 18

Ivermectin

Question 19

Inhibits microtubules synthesis and function?

Answer 19

-bendazole

Question 20

Activates parasitic nicotinic receptors, causing worm paralysis?

Answer 20

Pyrantel pamoate

Question 21

Increases cell Ca uptake, causing parasite contraction and paralysis?

Answer 21

Praziquantel