Antibiotic Man Primary Care Flashcards
When to give antibiotics for suspected meningitis
Give antibiotics if non-blanching rash, in combination with signs of meningism or sepsis, and time permits.
If time transfer is > 1 hour
What antibiotics are given for meningitis
Benzylpenicillin (IV/IM) 1.2g or if known anaphylaxis Cefotaxime 2g (IV/IM)
Meningitis prophylaxis for contacts
Ciprofloxacin
Orbital cellulitis
transfer to hospital immediately
Ceftriaxone IV 2g bd + Flucloxacillin IV 2g qds + Metronidazole IV 500mg tds (Penicillin allergy: seek advice)
Step down to Co-amoxiclav PO 625mg tds (10-14 days total)
Ophthalmic shingles
Start treatment up to 7 days after onset of rash
Refer to ophthalmology if eye involvement
Aciclovir 800mg 5 times daily or valaciclivor 1g tds (7 days) + lubricating eye drops if lesions near eyelid
Dental abscess
Penicillin V 500mg qds or metronidazole 4000mg tds (5 days)
tonsilitis/pharyngitis/sore throat
if >/= 4 on FeverPain
1st line- penicillin V 1g bd or 500mg qds (5 days)
2nd line- clarithromycin 500mg bd (5 days)
Unable to swallow: Benzylpenicillin IV 1.2g qds (penicillin allergy: clarithromycin IV 500mg bd)
Sinusitis
If ≤10 days symptoms there is no benefit from antibiotics unless clear evidence of systemic illness. If >10 days multiple or worsening symptoms consider back up antibiotic.
1st LINE Penicillin V 500mg qds or 1g bd (5 days)
2nd LINE Doxycycline 200mg day 1 then 100mg daily (5 days total)
Epiglottitis/supraglottitis
medical emergency- hospital transfer
Otitis media
Most cases will resolve without antibiotics and if used, they generally reduce symptom duration by <1 day. Consider antibiotics if otorrhoea present.
1st LINE Amoxicillin 500mg tds
2nd LINE Clarithromycin 500mg bd (5 days)
Otitis externa
Provide information on aural care. Mild – do not swab. Acetic acid 2% tds (EarCalm®) continuing for 2 days after
resolution (max 7 days). Moderate – do not swab. Sofradex® or Otomize® tds.
Severe- seek ENT guidance
Oral candidiasis
1ST LINE Miconazole gel qds or Nystatin 1ml qds
2ND LINE Fluconazole 50mg daily (Immunocompromised 100mg) (7 days)
*Clindamycin oral dosing
<50kg 300mg tds
50-90kg 450mg tds
>90kg or very severe illness 600mg tds or 450mg
Peritonsilar cellulitis
Benzylpenicillin IV 1.2g qds or Penicillin V oral 500mg qds or 1g bd.
Total duration IV/PO: 10 days
Penicillin allergy: Clindamycin* oral (10 days)
If unable to swallow IV Clindamycin 600mg – 1.2g qds
Supraglottitis
Ceftriaxone IV 2g od
Send blood cultures
Step down to Co-amoxiclav PO 625mg tds
(or in penicillin allergy: Doxycycline PO 100mg bd +
Metronidazole 400mg tds)
Post tonsillectomy haemorhage
If evidence of infection Amoxicillin IV 1g tds or Clarithromycin IV 500mg bd
Switch to oral Amoxicillin 500mg tds or Clarithromycin 500mg bd as soon as possible
Duration: 7 days total IV/PO
Consider use of tranexamic acid if no evidence of infection
acute rhinosinusitis
Penicillin V oral 500mg qds or 1g bd (7 days)
Penicillin allergy: Doxycycline 200mg on day 1 then 100mg thereafter (7 days)
Epistaxis
If packing has been in for >48hours – Flucloxacillin PO 1g qds – STOP when packing removed