anti fungal and anti viral drugs Flashcards

1
Q

does antibiotics have action on fungi and fungal infections

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the subdivisions of of fungi

A

yeasts and filamentous fungi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what does polyene drugs bind to?

A

ergosterol present in the fungal cell wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the reason for polyenes toxicity

A

it binds to other sterols in mammilian cell membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

are polyenes active against fungi

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is the only drug available for intravenous use and is used for the treatment of serious
systemic fungal infection

A

Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

are azoles affective against yeast infections?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what suppresses ergosterol synthesis

A

azoles and allylamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the only allylamine and what is it active against

A

terbinafine and dermatophyte infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what inhibits the synthesis of glucan polysaccharides

A

echinocandins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

do antibiotics have action against viruses?

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what does virucidal mean

A

kills virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what does virustatic mean

A

inhibit growth and/or replication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

is there virucidal or virustatic agents?

A

all virustatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

whats an anti-herpes drug?

A

aciclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how many drugs are combined for HIV

A

3

17
Q

what protein is used for chronic hep B and C

A

interferon a

18
Q

what drugs are used for viral respiratory infections?

A

zanamivir and oseltamivir