anti fungal and anti viral drugs Flashcards
does antibiotics have action on fungi and fungal infections
no
what are the subdivisions of of fungi
yeasts and filamentous fungi
what does polyene drugs bind to?
ergosterol present in the fungal cell wall
what is the reason for polyenes toxicity
it binds to other sterols in mammilian cell membranes
are polyenes active against fungi
yes
what is the only drug available for intravenous use and is used for the treatment of serious
systemic fungal infection
Amphotericin B
are azoles affective against yeast infections?
yes
what suppresses ergosterol synthesis
azoles and allylamines
what is the only allylamine and what is it active against
terbinafine and dermatophyte infections
what inhibits the synthesis of glucan polysaccharides
echinocandins
do antibiotics have action against viruses?
no
what does virucidal mean
kills virus
what does virustatic mean
inhibit growth and/or replication
is there virucidal or virustatic agents?
all virustatic
whats an anti-herpes drug?
aciclovir