anatomy of cell Flashcards
common features of the cell
outer membrane, inner cytosol, cytoskeleton, organelles, inclusions
plasma membrane
phospholipids. contains integral proteins. gives cell ability to exocytose and endocytos materials out of membrane
inclusions
dispensable, may only be present as transients. represents components synthesised in cell itself or taken from extracellular environment
what are cytoskeletons made of
set of filamentous cytosolic proteins
3 classes of cytosolic proteins
microfilaments, intermediate, microtubules
what are microfilaments
made of protein actin. actin molecules can assemble into filaments that can later dissociate. very dynamic
intermediate filament
made of 6 proteins that vary in cell types. bind intracellular elements together and to membrane. more than 50 types
what are microtubules
made of 2 tubulin proteins. hollow, originate from centrosome, include stabilising proteins (MAPs), can assemble and disassemble
nucleus
contains chromosomes, mRNA and tRNA transcribed in nucleus, rRNA transcribed in nucleolus. contains euchromatin and heterochromatin
euchromatin
DNA dispersed and actively undergoing transcription
heterochromatin
DNA highly condensed and not active
ribosomes
formed in nucleolus, important role in protein synthesis, each ribosome made of subunit that binds RNA. and a large unit that catalyses formation of peptide bonds
ER
forms network of membrane bound compartments in cell. 2 types SER and RER
RER
Studded w ribosomes, vital in protein synthesis, amount of RER varies in cell types
SER
continues processing proteins, site of lipid synthesis, most cells contain little SER
golgi
golgi manages modification and packaging of macromolecules synthesised in ER. Adds sugars, cleaves proteins
mitochondria
composed of inner and outer membrane, inner folded to increase surface area. power generators of the cell. generate ATP, contain own DNA
intercellular junctions
specialised membrane structures which link individual cells together into a functional unit, prominent in epithelia
occluding junctions
link cells to form a diffusion barrier. known as tight junctions
anchoring junctions
provide strength, link submembrane actin bundles of adjacent cells together. common in skin
communicating junctions
selective diffusion of molecules between cells. pores are produced by connexon proteins. found in epithelia and some smooth muscle. known as gap junctions
junctional complex
several types of junctions found in certain epithelial tissues
transport in and out of cell
diffusion, transport proteins, incorporation into vesicles (vesicular transport)
vesicular transport : endocytosis
material from outside can come in. cell membrane invaginates, fuses and newly made endosomes bud into cell. process is receptor mediated. exocytosis is opposite