Amino Acids Flashcards

1
Q

which one is the Imino Acid

A

proline

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2
Q

curly hair is abundant in which amino acid

A

proline

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3
Q

pka less then 7 is

A

acidic

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4
Q

pka more then 7 is

A

basic

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5
Q

charged or polar means

A

soluble

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6
Q

uncharges or neutral means

A

bioavialble

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7
Q

losing a H+ means

A

dissociation

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8
Q

which is the amino acid with the closet pka to the body

A

histidine (6.2)

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9
Q

what is caustic (corrosive) ingestion

A

when you ingest wither a strong acid or a strong base

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10
Q

what should you not give to someone after they have ingested a strong acid

A

syrup of Ipecac (vomiting inducer) because it will burn them again on the way up

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11
Q

chronic complication of strong acid/base ingestions

A

structure formation

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12
Q

how to treat myoglobin

A

bicarb

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13
Q

acid used in medicine

A

ammonia chloride NH4CL

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14
Q

base used in medicine

A

bicarb

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15
Q

anode

A

the positive electrode (where negative particles move towards)

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16
Q

cathode

A

the neg electrode ( where positive particles move towards)

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17
Q

what experiment determines pka

A

titration

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18
Q

what is the smallest amino acid with no chiral carbons and is the inhibitory NT of the spinal cord

A

glycine

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19
Q

what are the aromatic (big/bulky) AA’s

A

Phenylalanine
Tyrosine
Tryptophan

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20
Q

what are the basic amino acids

A

leucine and arginine

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21
Q

what enzyme recognizes leucine and arginine

A

trypsin

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22
Q

what are the acidic AA’s

A

Aspartic Acid and Glutamic Acid

23
Q

which AA is in the NMDA pathway and helps you geel gooooood

A

aspartate

24
Q

what blocks the NMDA pathway, therefore blocking ASPARTATE

A

Glutamate

25
Q

what blocks glutamate and allows the NMDA pathway to function

A

Memantine

26
Q

what amino acids have sulfur bonds

A

Cysteine and Methionine

27
Q

what amino acids have N-bonds

A

Asparagine and Glutamine

28
Q

what amino acids have o binds

A

Serine
Threonine
Tyrosine

29
Q

what AA is found in the active site of most enzymes

A

serine

30
Q

what are the branched chain AA

A

Leucine
Isoleucine
Valine

31
Q

what 4 hormones have a lot of disulfide bonds

A

insulin
inhibit
GH
prolactin

32
Q

what AA makes catecholamines

A

tyrosine

33
Q

what AA makes Serotonin

A

tryptophan

34
Q

what are the ketogenic AA and what does that mean

A

Leucine
Lysine

means they are made from ACOA and are broken down back into it to make AA’s

35
Q

what are the AA’s that are both glycogenic and ketogenic

A

Phenylalanine
isoleucine
threonine
tryptophan

36
Q

name the 10 essential AA’s

A
Phenylalanine
valine
threonine
tryptophan 
isoleucine
methionine
histidine
arginine
leucine
lysine
37
Q

methionine makes

A

cysteine

38
Q

phenylalanine makes

A

tyrosine

39
Q

inhibitory NT of the brain

A

GABA

40
Q

order of energy utilization when starving

A

serum glucose (2-4 hours) – epinephrine and glucagon
liver glycogen (1.5d)– epinephrine and glucagon
proteolysis for gluconeoenesis– Cortisol and GH (prot.) and glucagon
lipolysis – glucagon
ketogenisis – glucagon

41
Q

deficient enzyme in PKU

A

Phenylalanine hydroxyls

42
Q

problem in PKU

A

unable to make tyrosine so can’t make catecholamines or melanin

43
Q

what is the guthrie test and what does it measur

A

test to see if the child has PKU and it measures the amounts of phenyl acetate and phylpyruvate

44
Q

when should mother with PKU have restricted diet

A

first 8 weeks while brian is forming

45
Q

what is detected in screening for CAD

A

17-hydroxylase

46
Q

what is deficient in CAD

A

21 hydroxylase

47
Q

screening test for celiac sprue

A

transglutaminase

48
Q

screening test for CF

A

immunoreactive trypsin

49
Q

deficient in albinism

A

tyrosinase

50
Q

cause of vitiligo

A

autoimmune destruction of melanocytes

51
Q

deficient in Alkaptonuria

A

homogentisic acid oxidase ( increase seen in tyrosine)

52
Q

problem in maple syrup urine disease

A

build up of branch chain amino acids because the collecting ducts in the kidney cannot transport them

53
Q

defect in Cysteinuria

A

defect in the renal transport of Cysteine, ornithine, lysine and arginine

54
Q

crystal seen in the urine of someone with cysteinuria

A

hexagonal/coffin shaped