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Uworld_sitr > Amino Acids > Flashcards

Amino Acids Flashcards

1
Q

which one is the Imino Acid

A

proline

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2
Q

curly hair is abundant in which amino acid

A

proline

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3
Q

pka less then 7 is

A

acidic

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4
Q

pka more then 7 is

A

basic

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5
Q

charged or polar means

A

soluble

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6
Q

uncharges or neutral means

A

bioavialble

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7
Q

losing a H+ means

A

dissociation

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8
Q

which is the amino acid with the closet pka to the body

A

histidine (6.2)

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9
Q

what is caustic (corrosive) ingestion

A

when you ingest wither a strong acid or a strong base

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10
Q

what should you not give to someone after they have ingested a strong acid

A

syrup of Ipecac (vomiting inducer) because it will burn them again on the way up

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11
Q

chronic complication of strong acid/base ingestions

A

structure formation

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12
Q

how to treat myoglobin

A

bicarb

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13
Q

acid used in medicine

A

ammonia chloride NH4CL

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14
Q

base used in medicine

A

bicarb

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15
Q

anode

A

the positive electrode (where negative particles move towards)

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16
Q

cathode

A

the neg electrode ( where positive particles move towards)

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17
Q

what experiment determines pka

A

titration

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18
Q

what is the smallest amino acid with no chiral carbons and is the inhibitory NT of the spinal cord

A

glycine

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19
Q

what are the aromatic (big/bulky) AA’s

A

Phenylalanine
Tyrosine
Tryptophan

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20
Q

what are the basic amino acids

A

leucine and arginine

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21
Q

what enzyme recognizes leucine and arginine

A

trypsin

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22
Q

what are the acidic AA’s

A

Aspartic Acid and Glutamic Acid

23
Q

which AA is in the NMDA pathway and helps you geel gooooood

24
Q

what blocks the NMDA pathway, therefore blocking ASPARTATE

25
what blocks glutamate and allows the NMDA pathway to function
Memantine
26
what amino acids have sulfur bonds
Cysteine and Methionine
27
what amino acids have N-bonds
Asparagine and Glutamine
28
what amino acids have o binds
Serine Threonine Tyrosine
29
what AA is found in the active site of most enzymes
serine
30
what are the branched chain AA
Leucine Isoleucine Valine
31
what 4 hormones have a lot of disulfide bonds
insulin inhibit GH prolactin
32
what AA makes catecholamines
tyrosine
33
what AA makes Serotonin
tryptophan
34
what are the ketogenic AA and what does that mean
Leucine Lysine means they are made from ACOA and are broken down back into it to make AA's
35
what are the AA's that are both glycogenic and ketogenic
Phenylalanine isoleucine threonine tryptophan
36
name the 10 essential AA's
``` Phenylalanine valine threonine tryptophan isoleucine methionine histidine arginine leucine lysine ```
37
methionine makes
cysteine
38
phenylalanine makes
tyrosine
39
inhibitory NT of the brain
GABA
40
order of energy utilization when starving
serum glucose (2-4 hours) -- epinephrine and glucagon liver glycogen (1.5d)-- epinephrine and glucagon proteolysis for gluconeoenesis-- Cortisol and GH (prot.) and glucagon lipolysis -- glucagon ketogenisis -- glucagon
41
deficient enzyme in PKU
Phenylalanine hydroxyls
42
problem in PKU
unable to make tyrosine so can't make catecholamines or melanin
43
what is the guthrie test and what does it measur
test to see if the child has PKU and it measures the amounts of phenyl acetate and phylpyruvate
44
when should mother with PKU have restricted diet
first 8 weeks while brian is forming
45
what is detected in screening for CAD
17-hydroxylase
46
what is deficient in CAD
21 hydroxylase
47
screening test for celiac sprue
transglutaminase
48
screening test for CF
immunoreactive trypsin
49
deficient in albinism
tyrosinase
50
cause of vitiligo
autoimmune destruction of melanocytes
51
deficient in Alkaptonuria
homogentisic acid oxidase ( increase seen in tyrosine)
52
problem in maple syrup urine disease
build up of branch chain amino acids because the collecting ducts in the kidney cannot transport them
53
defect in Cysteinuria
defect in the renal transport of Cysteine, ornithine, lysine and arginine
54
crystal seen in the urine of someone with cysteinuria
hexagonal/coffin shaped

Uworld_sitr (42 decks)

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