Amino Acids Flashcards
which one is the Imino Acid
proline
curly hair is abundant in which amino acid
proline
pka less then 7 is
acidic
pka more then 7 is
basic
charged or polar means
soluble
uncharges or neutral means
bioavialble
losing a H+ means
dissociation
which is the amino acid with the closet pka to the body
histidine (6.2)
what is caustic (corrosive) ingestion
when you ingest wither a strong acid or a strong base
what should you not give to someone after they have ingested a strong acid
syrup of Ipecac (vomiting inducer) because it will burn them again on the way up
chronic complication of strong acid/base ingestions
structure formation
how to treat myoglobin
bicarb
acid used in medicine
ammonia chloride NH4CL
base used in medicine
bicarb
anode
the positive electrode (where negative particles move towards)
cathode
the neg electrode ( where positive particles move towards)
what experiment determines pka
titration
what is the smallest amino acid with no chiral carbons and is the inhibitory NT of the spinal cord
glycine
what are the aromatic (big/bulky) AA’s
Phenylalanine
Tyrosine
Tryptophan
what are the basic amino acids
leucine and arginine
what enzyme recognizes leucine and arginine
trypsin
what are the acidic AA’s
Aspartic Acid and Glutamic Acid
which AA is in the NMDA pathway and helps you geel gooooood
aspartate
what blocks the NMDA pathway, therefore blocking ASPARTATE
Glutamate
what blocks glutamate and allows the NMDA pathway to function
Memantine
what amino acids have sulfur bonds
Cysteine and Methionine
what amino acids have N-bonds
Asparagine and Glutamine
what amino acids have o binds
Serine
Threonine
Tyrosine
what AA is found in the active site of most enzymes
serine
what are the branched chain AA
Leucine
Isoleucine
Valine
what 4 hormones have a lot of disulfide bonds
insulin
inhibit
GH
prolactin
what AA makes catecholamines
tyrosine
what AA makes Serotonin
tryptophan
what are the ketogenic AA and what does that mean
Leucine
Lysine
means they are made from ACOA and are broken down back into it to make AA’s
what are the AA’s that are both glycogenic and ketogenic
Phenylalanine
isoleucine
threonine
tryptophan
name the 10 essential AA’s
Phenylalanine valine threonine tryptophan isoleucine methionine histidine arginine leucine lysine
methionine makes
cysteine
phenylalanine makes
tyrosine
inhibitory NT of the brain
GABA
order of energy utilization when starving
serum glucose (2-4 hours) – epinephrine and glucagon
liver glycogen (1.5d)– epinephrine and glucagon
proteolysis for gluconeoenesis– Cortisol and GH (prot.) and glucagon
lipolysis – glucagon
ketogenisis – glucagon
deficient enzyme in PKU
Phenylalanine hydroxyls
problem in PKU
unable to make tyrosine so can’t make catecholamines or melanin
what is the guthrie test and what does it measur
test to see if the child has PKU and it measures the amounts of phenyl acetate and phylpyruvate
when should mother with PKU have restricted diet
first 8 weeks while brian is forming
what is detected in screening for CAD
17-hydroxylase
what is deficient in CAD
21 hydroxylase
screening test for celiac sprue
transglutaminase
screening test for CF
immunoreactive trypsin
deficient in albinism
tyrosinase
cause of vitiligo
autoimmune destruction of melanocytes
deficient in Alkaptonuria
homogentisic acid oxidase ( increase seen in tyrosine)
problem in maple syrup urine disease
build up of branch chain amino acids because the collecting ducts in the kidney cannot transport them
defect in Cysteinuria
defect in the renal transport of Cysteine, ornithine, lysine and arginine
crystal seen in the urine of someone with cysteinuria
hexagonal/coffin shaped
