amboss incorrects Flashcards
false incorrets of vdrl
h viral infections, rheumatic fever, lupus, or leprosy.
white lump curd ike discharge in vagina
vulvovaginitis
an old woman has high inhibin b what could the diagnosis be
granulosa cell tumor
contraindications of ocps
OCPs are contraindicated in women who have migraines with aura, smoke cigarettes above the age of 35 years, or have a history of stroke, thromboembolism, breast cancer, or liver disease.
histology of an oocyte
surrounded by flat granulosa cells, stroma surrounds granulosa
when does meiosis complete in an ococyte
Primary oocyte arrest occurs in prophase I of meiosis I (think PROphase = PRior to Ovulation).
Secondary oocyte arrest occurs in metaphase II of meiosis II (think METaphase = before egg MET sperm).
female embryonic deriative of gubarnaculum
Ovarian ligament
what is the purpose of giving ocps in pcos
increases SHBG binds to testosterone decreases androgens
how does progesterone act
it arrests endometrium at certain stage
raloxifene contraindications
previous throm
does endometriois increase risk of malignancy
yes
what is round ligament responsible for
anteverson antiflexion of uterus
what is artery of sampson
anatomosis in uterine and ovarian artery
what is a dermoid cyst
A mature cystic teratoma that can occur on the head, the neck, spine, cranium, and in the abdomen (most common ovarian tumor in females). Cysts typically become symptomatic as they grow in size. They are treated with complete surgical excision.
how tod istinguish uterine prolapse from cytocele
urinary symotoms same, but cystocele has vaginal protusion uterine prolapse has decent of utrus
gestial sac visualistion and dilated cervix is
Visualization of the gestational sac and dilatation of the cervix in a woman at only 31 weeks’ gestation would be concerning for preterm labor. A
causes of congenital torticollis
., secondary to clavicular fracture, cervical fracture, or dislocation of C1/C2 with spastic contracture of the sternocleidomastoid muscle
defective intraellular transport of meanosomes to keratinocyes
post inflammatory hypopigmenation
a pregnant with prexisitng heart disease
systolic benign diastolic path
vaterl association leads o
polyhydraminos
best drug for treating postpartum hemorrhage
oxytocin
small pelvis shallow intragleutal cleft maternal diabeties
caudal regression syndrme
which rrna trasncript is transcribed outside the nucleous
rrna transcrpit 5s rna poly 3
i give a person azothoprine and he has xanthine oxidase deficiency
no secretion of thiouric acid azothoprine completely blocks HGPRT, since it blocks HGPRT no salvage= increased toxicity
uti by klebseilla causes what colour change of agar
greent o purple
pyrdazimide tb drug
requires acidic ph to be activated so its only functional within lysosomes not exxtracellular
pyrdazimide tb drug
requires acidic ph to be activated so its only functional within lysosomes not exxtracellular
which is the only trna that does not bind to A site
Methonine
what is the function of N fromylmethonine
it codes for chemotaxis of neutrophils
where does n and o glycosylation occur
n occurs in rer o occurs in golgi in n aspargine is involved in o serine and theorine
which aminoacid is excised due to post transitaional modification
The first methionine is subsequently removed by an N-terminal peptidase as a part of the cotranslational or posttranslational modification, while all other sulfur-containing amino acids are not excised
which is inovled in methylatiuon
SAm
how does the process of N acetylation work
its simple aminoacid methionine is removed by aminoacid peptidase, then replaced by acetyl group by acetyl coa via acetyl transferase this always happens
aceylation also occurs in lysine residudes of histones
what is the moa of ampicillin gentamicin synergestic effect
it makes bacterial cell wall more permeable
difference between elastin and collagen synthesis
elastin doesnt undergo glyscosylation no hydroxylastion and lysine is crosslinked due to lysl oxidase what is solar elastossis? what is transglutaminase and lysloxidase
errors in ubiquintation
parkinson monoubq vs polyubq mom is for trafficking poly is for degradation
glucose 6 p to glucose
in ser
how do glucorticoids cause osteoporosis
apoptosis of osteocytes, inhibits differenction of mesenchymal cells to osteoblasts
high glucorticoid support RANKL synthesis by preosteoblasts
inhibits androgens and estrogens
osgood schatler disease
Overuse (especially sports involving sprinting and jumping) during the ossification period (adolescence) → excessive strain and repeated avulsion of the patellar ligament on the tibial tuberosity → inflammation → traction apophysiti
chronic inflammation of patella
secondary ossification of the tibial tuberosity → detachment of the apophysis → subsequent callous formation during the healing process → pronounced tibial tubercle [1]
chronic inflammation of patella
secondary ossification of the tibial tuberosity → detachment of the apophysis → subsequent callous formation during the healing process → pronounced tibial tubercle [1]
myophosphrylase deficiency lab findings and explain the why
flat venous lactate curve with exaggerated elevations in blood ammonia during exer
because glucose not produced to overwhelm the krebs cycle to form pyruvate which causes lactate to form
histopath of ewings
A t(11;22) chromosomal translocation, resulting in expression of fusion protein EWS-FLI 1, several layers of new bine around lytic bone
conversion of prostglandin H2 to txa2
thrombonxane synthase inhibtied by anti thrombitc drugs
which drugs inhibti DHF
pyrmethimee, trimethoprim and methotrexate
what is codmans triangle
basically when osteosarcomas bcome malignant they grow into the periosteum leading to periosteal reactions (these periosteal reaction are know as bony spicules giving it a suburst appearnence)
where do chrondromsarcomas commonly occur
chondrosarcomas commonly present with osteolytic lesions involving the pelvis, spine, or shoulder girdle and mainly occur in patients over the age of 50 years.
giant cell osteomas
they arise promixal to the knee and is associated with age 20 however osteosarcoma age 15
what is ragged muscle fibres
compensatory proliferation of mitochondria in gomori stain
polymyositis vs dermatomysositis
poly is endomysial inflammation, whereas dermato is perimysial
poly is cd8 t whereas dermato is cd4
cutaneus manifestaion of dem
mechanis hand, externsor papules symmetrically distributed,, helitrope rash
pagets vs osteopetoris
“bowing of the legs” is a buzzword for Paget’s disease, and it also tends to be more localized (whereas Osteopetrosis is diffuse). The warmth over the shins is also a clue towards Paget’s because of the increased vascularity (remember how it’s associated with AV shunts/high output
high pth what is changed
subperiosteal changes with cysts
osteoporosis what is changed
trabeculae
when is woven bone formed
Formed during embryonic development, after fractures (secondary bone healing), and in Paget disease
trabecular bone vs cortical bone
it is the ends of the bone which resists tensile strength
what are the muscle fibre changes in hypothyroid myopathy and what is elevated
Hypothyroid myopathy is characterized by noninflammatory type II muscle fiber atrophy with relative type I muscle fiber hypertrophy. This condition may also manifest with proximal muscle weakness and elevated creatine kinase,
why osteomyletits is common in children and why only in the metaphysis
blood is slow in metaphysis creates a sharp lopp whichcauses stasis of blood
why we have involvurum what is it and what is sequestrem
Inflammation in the marrow causes increased intramedullary pressure, which forces the exudate into the cortex, where it can rupture through the periosteum. More than 80% of cases of hematogenous osteomyelitis occur in the long bones, the femur and tibia being the most common, and cases usually originate in the metaphyses.