Agranular Leukocytes, Blood Typing Flashcards
Lymphocytes are ___% of leukocytes.
30%
Describe the nucleus of a lymphocyte.
Spherical, slightly dented
Describe the size of lymphocytes
2 sizes: Small 5-8 μm and large 14-17 μm
In lymphocytes, a small rim of ______ is visible.
cytoplasm
What are the 2 types of lymphocytes?
T-Cells
B-Cells
Can T-Cells and B-Cells be visually differentiated?
No (Not at our level, anyways)
Lymphocytes originate in ___________ and are non-_________ in their action
Bone marrow
Non-phagocytic
How do T-Cell act?
Acts directly against infected cell
What are the two kinds of immunity?
Cell-mediated immunity
Humoral immunity
What is cell-mediated immunity?
cell-to-cell defense
Which leukocyte confers cell-mediated immunity?
T-Cells
What is humoral immunity?
Blood-borne immunity
Which leukocyte confers humoral immunity?
B-Cells
What do B-Cells turn into?
Plasma cells
What do plasma cells produce?
Antibodies
Monocytes are __% of leukocytes
2%
Describe the nucleus of a monocyte
Large, or kidney shaped
How much cytoplasm is visible in monocytes?
Lots. More than a leukocyte
What do monocytes differentiate into?
Differentiate into macrophages (Big eater of things)
How and where are monocytes transported?
Blood carries monocytes to tissue where they migrate out and become macrophages
What is the mechanism of monocytes?
Phagocytize pathogens, dead neutrophils, and debris
What is an APC?
Antigen presenting cell
How are monocytes APCs?
Present fragments of antigens on their surface to alert the immune system
What is the first leukocyte to arrive at the site of damage? What follows, and in what number?
Take longer to arrive at damage site (after neutrophils), but monocytes come in greater numbers
What is a chemical drawing cells to inflamed tissue?
Chemotaxis
What is it when cells slip between endothelial cells to enter/exit the bloodstream?
Diapedesis