Ageing and Frailty Flashcards
‘Elderly’ is defined as
≥ 65 yo
What is the Rectagularisation of Survival Curves?
Achieving one’s predicted life expectancy thanks to improvements in health and hygiene
Successful ageing is defined as…
Changes due to the ageing process without any disease, personal choices or lifestyle factors
Usual Ageing is
Ageing + Environment + Personal Choices + Illness
Frailty is
the diminished ability to carry out the important practical and social activities of daily living
Frailty is related with
Chronic activation of the immune system
What cytokines are related to catabolism and anorexia?
TNF alpha and IL-6
Cytokine which [ ] is related with increased mortality rate and predictive value of functional decline?
IL-6
Sarcopenia is…
Loss of muscle due to ageing
some of the causes of sarcopenia are
Decreased muscle nerve supply (loss of anterior horn cells)
decreased hormone levels (GH,IGF-1,oestrogen,testosterone)
inflammatory markers
muscle mass decreases since you are 30
What is the main type of fibre loss in sarcopenia?
Type 2: fast fibres
What is a medical syndrome?
signs + symptoms associated with morbid process
Multiple symptoms 1 pathogenic pathway
Geriatric Syndrome is…
symptoms or complex of Sx w high prevalence in geriatrics
multiple diseases involved and Risk factors
if the condition starts with ‘I’ think of
Geriatric Syndrome
Iatrogenic changes, incontinence, immobility, impaired balance, impaired cognition
Define iatrogenic
Illness caused by medical treatment
