AG2-Exam 4 Flashcards

1
Q

What will cause a false positive HIV result with a fast rapid test?

A

pregnant, recent flu shot, autoimmune disorder

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2
Q

What is HIV stage 1

A

acute response

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3
Q

HIV stage 2

A

chronic

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4
Q

HIV stage 3

A

final, most serious

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5
Q

most infectious stage, no change in CD4 count (HIV)

A

incubation

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6
Q

fever, weight loss, diarrhea, infections, CD4T < 500

A

crisis

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7
Q

Sx: fevers, HA, rash , ST, photophobia, msl aches.
Signs: CD4T WNL, lymph node involvement

A

early and latent

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8
Q

What are the 3 antibody screening tests for HIV?

A
  1. enzyme-linked immunosorbent assay (ELISA or EIA)
  2. Western Blot
  3. Immunofluorescence assay (IFA)
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9
Q

criteria for AIDS defining illness

A

CD4 + T cell count < 200 cells + infection

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10
Q

Malignancy features with AIDS

A

Burkett’s lymphoma

Kaposi’s sarcoma

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11
Q

GI features with AIDS

A

wasting syndrome

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12
Q

Fungal infections with AIDS

A

PCP, Valley Fever, histoplasmosis

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13
Q

sx of Valley Fever

A

HA, confusion, neck stiffness, photophobia, rash

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14
Q

Viral infections with AIDS

A

CMV, Progressive multifocal leukoencephalopathy, Herpes simplex, extrapulmonary cryptococcosis

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15
Q

Protozoal infections with AIDS

A

toxoplasmosis, intestinal isopsoriasis, cryptosporidiosis

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16
Q

Bacterial infections with AIDS

A

TB, recurrent salmonella, septicemia

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17
Q

Interventions to prevent infection with HIV

A

monitor VS, promote immunizations and ART regimen adherence

18
Q

Example of PrEP med

19
Q

Example of PEP med

A

cART (combined antiretroviral therapy)

20
Q

Infection prevention in the home for AIDS

A
  • Keep the home environment clean
  • Wash dishes in hot water using a dishwasher if available.
  • Avoid cleaning pet litter boxes.
  • Avoid people who are sick.
  • Avoid raw foods and undercooked foods.
21
Q

Timeframe that PEP needs to be taken by

A

within 72 hours after possible exposure

22
Q

Which cells does HIV target

A

CD4 T lymphocytes

23
Q

What is a normal CD4 T cell count?

24
Q

What is antiretroviral therapy?

A

daily use of a combination of HIV medicines to treat HIV. Does not cure HIV.

25
What does ART do?
- Reduces the amt of HIV in the body. - Reduces the risk of HIV transmission. - Prevents HIV from advancing to AIDS. - Protects the immune system
26
Types of hypersensitivity reactions
1. Type 1 IgE mediated 2. Type II Cytotoxic 3. Type III Immune complex 4. Type IV Cell mediated
27
What is a type 1 hypersensitivity
IgE mediated
28
How can allergens be contacted
inhaled, ingested, injected, skin or mucous membranes
29
What is a type 2 hypersensitivity
cytotoxic (toxic to cells)
30
patho of type 2 hypersensitivity
body makes autoantibodies IgG directed against self cells that have some form of foreign protein attached to them
31
Example of type 2 hypersensitivity
ABO incompatibility with blood product transfusions; Goodpasture syndrome; and Myasthenia gravis.
32
What is a type 3 hypersensitivity reaction
immune complex reactions
33
patho of a type 3 hypersensitivity reaction
results from excess antigens causing immune complexes to form in the blood. Most autoimmune disorders are caused by this.
34
Examples of Type 3 hypersensitivity
SLE, RA
35
What is a type IV hypersensitivity
delayed hypersensitivity. Occurs hours to days after exposure.
36
patho of type 4 hypersensitivity
sensitized T lymphocytes (T cells) from a previous exposure are activated triggering the excessive responses of macrophages and release of chemical mediators. Antibodies and complement are not involved.
37
Example of type IV hypersensitivity
dermatitis
38
Medications for SLE
NSAIDs, corticosteroids, immunosuppressants, antimalarial (hydroxychloroquine)
39
Serum diagnostics testing for SLE
ANA, CBC, ESR, serum complement levels (C3,C4)
40
Generalized HIV symptoms
chills, fever, rash, anorexia, nausea, weight loss, weakness, fatigue, HA, ST, night sweats