Active Tuberculosis Flashcards
Why does the second phase occur?
When the patients immune system cannot contain the disease when it first arrives in the lungs.
Why may the body not be able to contain the disease?
Number of bacteria may be too great.
Old infection may break out if the immune system is no longer working properly.
Why may the activity of the immune system be reduced?
- Old age/young it is less able to respond quickly to pathogens.
- Malnutrition and poor living conditions affect the immune system.
- AIDS, targets WBC and reduces patients ability to fight any infection.
What is active TB called in the lungs?
Respiratory pulmonary TB
What does the bacteria do to the lungs?
Bacteria multiply rapidly ad destroy the lung tissue, creating holes or cavities.
What are the symptoms of Active TB
Coughing; the patient may cough up blood.
Shortness of breath
Loss of appetite and weight loss
Fever and extreme fatigue
FEVER: What may the person infected with TB experience?
Fever and night sweats
Why may the individual experience fever and night sweats?
Inflammatory response
Fever causing substances are released from neutrophils and macrophages.
What do the chemicals released from inflammatory response affect?
The hypothalamus and alter the set point for the core body temperature to a higher temperature?
What part of the body warms the body up to a new set point? Why is the consequence of this?
Effects act and warm the body up to a new set temperature. The patient has a high fever, with a temperature region of 40.5 c
What is the effect of a raised body temperature?
Enhances immune function and phagocytosis.
Bacteria and viruses reproduce more slowly at higher temperatures.
Is TB temperature sensitve?
Yes it will stop reproducing at temperatures above 42
If the human body temp is above 40 what happens to enzymes?
They are increasingly denatured.