7.2 Getting rid of lactate and the effect of lactate Flashcards
What groups do many of the amino acids that make up enzymes have?
Positively or negatively charged groups.
Where do hydrogen ions from the lactic acid accumulate?
In the cyptoplasm
What do the hydrogen ions from the lactate do?
They neutralize the negatively charged groups in the active site of the enzyme.
What will be affected and what is the consequence of this?
The attraction between charged groups on the substrate and in the active site will be affected. The substrate may no longer bind to the enzymes active site.
Summary: What does do the hydrogen ions prevent the substrate from doing?
- Hydrogen ions
- Prevent the substrate from being attracted to
- Charged groups in the active site.
What can lactate build up lead to in the muscle of an athlete?
Muscle cramp.
After a period of anaerobic respiration and the lactate is converted back into pyruvate what is it oxidIsed directly to? What is the consequence of this?
Carbon dioxide and water via the Krebs Cycle and the electron transport chain therefore releasing energy to synthesis ATP.
What is greater than normal during the recovery period? What is this called?
Oxygen uptake is greater than normal during the recovery period and this excess oxygen requirement is called oxygen debt.
What is oxygen debt needed to do?
Needed to fuel the oxidation of lactate.
What could some lactate be converted back to besides pyruvate?
Into glycogen and store in the muscle or liver.
