action Flashcards

1
Q

difference between extensors and flexors

A

extensors extend a joint

flexors contract f

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2
Q

what 3 parts of the NS does action focus on

A

somatic - moving limbs on purpose

autonomic - unconscious inner body action

internal actions - switching thoughts

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3
Q

why is action an inverse problem

A

you start with a goal, and figure out what sequence of actions you can take to accomplish it

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4
Q

this chapter we went from top to bottom of action through diff brain and body structures - list them top to bottom

A

start with motor cortex
premotor and supplementary motor areas in prefrontal cortex
basal ganliga role in initiation
cerebellums role in coordination
spinal cord
muscles

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5
Q

what is motor equivalence

A

the ability to use different movement produced by either the same or different parts of the Boyd, to perform a task under different conditions

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6
Q

forward model

A

what will come of the result if I perform an action?

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7
Q

feed forward control

A

come up with a motor command, send it to muscles to perform, and that’s it - hope for the best.

fast but less accurate, so you may use it when speed is the most important thing

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8
Q

feedback control

A

come up with a motor command to send to muscles, perform action and compare what actually happens to what you were hoping was gonna happen

If you detect errors, you revise the motor command. Not just send commands and hope for the best, there is a continuous feedback loop of adjustment

slower but more accurate

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9
Q

if the input is the goal and the output is the motor command - what kind of model is it

A

inverse model

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10
Q

is feedback control an inverse model?

A

yes because it starts with goal state, and motor command as output. but through visual sensory we compare what happens with our goal and adjust if necessary - this part is a forward model

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11
Q

what common household item is a feedback control system

A

thermostat - tries to reach a heat, compares goal to actual temperature, simple feedback loop that makes adjustments

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12
Q

what role does the premotor cortex play

A

cognitive function - what my goal is and how will I accomplish that goal

high level goals and action planning

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13
Q

how long before an action occurs can we see planning activity (readiness potential) in the ipsa or contra lateral hemisphere premotor cortex

what about when they consciously note the decision to make the movement

A

contralateral because opposite sides control each other

as much as a second before movement occurs

when they consciously report to making the decision, the premotor cortex has already become active

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14
Q

the monkey study with spatail cues shows brain activity when monkey is planning for 2 actions - explain

A

has to pick one colour or the other based on the cue, neyrons are tuned to diff directions of movement
- baseline - all fire at same level
- sees which 2 movements it may have to do - these two start to fire more simultaneously
-cues disappear while memory is held in mind, neurons continue to fire
-cue of which movement to make is shown, one increases firing rate, and the other is inhibited below baseline
- knows what action to take but waiting for the go, neurons ramp up in preparation
- go cue, neurons have final burst to make the movement

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15
Q

what controls initiation or inhibition of movements

A

basal ganglia

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16
Q

how does BG initiate or inhibit movements

A

Cortico BasalGanglia Thalamo Cortical Loops

start in cortex, descend to BG, go to Thal, and then back to cortex

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17
Q

how does the BG know whether to initiate or inhibit a movement,

what else is it used for initiating besides motor actions

A

Reinforcement learning based on Dopamine from Substantia Nigra

also helps us switch thoughts or update memories, control emotion, relax or take action

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18
Q

steps of direct pathway

A

baseline - GPA and SNR actively inhibit thalamus w IPSPs causing thalamus to only send weak signals to cortex
- cortex send rep to striatum via Epsp
-striation fires more, sends stronger IPSP down the path
Striatum INHIBITS GPI and SNR
-so these 2 send weaker signal to thalamus than before
-release thalamus from inhibition

positive feedback loop
2 IPSP cancel each other out

19
Q

steps of indirect pathway

A

-cortex sends rep to striatum
-striatum ramps up inhibition of GPI
-inhibit GPI, released subthalamic nucleus from inhibition
-subthal fires more, sends EPSP to GPI and SNR
-these 2 inhibit the thalamus more
-thalamus sends back weak response to motor cortex

3 negatives = negative

20
Q

how can an NT like dopamine causes two different effects

A

different types of receptors on post neuron
D1 are excitated by dopamine
D2 are inhibited by dopamine

21
Q

list ways that CBGTC loop are used

A

emotions
motivational contorl
switching thoughts
remember or forget info
effort vs none
express or bottle emotins
eye movement

22
Q

what keeps movements coordinated

A

cerebellum

23
Q

where is white and grey matter in CB

A

buried white matter

surface of grey matter

24
Q

2 types of CB cells

A

granule
purkinje

25
Q

what are granule cells, their shape, where in the CB are they, their characteristics

A

granule are a sig part of neurons in brain

in small space of CB

have parallel fibres

run up and down horiz

long and synapse onto a lot of things

tend to connect with purkinje cells

26
Q

what are purkinje cells, characteristics, shape, where in CB are they

A

lots of dendrites
lots of input from other cells
each synapse is opp to adjust strength of connection

27
Q

what kind of model does the CB use

A

forward model

motor command as input and output is the predicted result
CB plays a role in error checking and feedback control
constant monitoring to see if actions need redirection to meet the goal

28
Q

missing slides

A

7-18 action

29
Q

what are central pattern generators

what study showed this

A

circuits in spinal cord that control repetitive consistent movements like walking. makes proper muscle fire at proper time

cat with severed SC walking on a treadmill

30
Q

limits to central pattern generators - cat treadmill

A

if cat saw something and wanted to run towards it - info couldn’t get to the hind legs

any top down volitional control or decision making depends on the brain

31
Q

role of lower motor neurons

A

they are in the spinal cord, their axons run out and synapse onto muscle fibres in our limbs in PNS

32
Q

what are muscle fibres

A

specialized cells, opposite of sensory receptors

muscle fibres convert neural input signals into a physical change in the world by contraction of MF (output)

33
Q

what are muslce spindles

A

sensory cells buried in muscle amongst MF

give us our sense of proprioception in our muscles

34
Q

how does the amount of muscle fibers motor neurosn synpse onto effect how we can control our muscles with precision

A

if you want fine control over your muscles, you have to have each lower motor neuron to synapse onto FEWER muscle fibres so you can control more precisely with muscle fibres are activated at any given time

if you follow this back to the cortex, we need more neurons there to control the lower motor neurons - this is why the part of motor cortex for hand is larger than the back - more detailed movement s needed

35
Q

the cortical magnification in the primary motor cortex firectly relates to the fact that

A

for fine motor control you need to have each motor neuron controlling only a small number of muscle fibers

36
Q

in single and mulit unit recording, what does the unit refer to

A

unit means single or multi neurons recording,

researches use the term unit when you put electrode in brain and record from it - it is hard to know if you are recording a single unit or not

37
Q

how is intracellular recording done

A

touching or inserting into an ind cell,

cell must be out of the animal - petri dish

not the type we are looking at

38
Q

how is extracellular recording done

is either ___ or ____

A

same tech as computer chips, pushed in brain tissue, near neurons but not IN any,

either
Invitro - petri dish
Invivo - intact animal while it does an action. plug on their head you can plug into to record the data

39
Q

extracellular recording is good for what 2 kinds of resolution

A

spatial - we know where in the brain the data is coming from rather than measuring from outside the brain

temporal - you know exactly when the activity occurs in time because we record AP down to the ms

40
Q

disadvantages of single cell recording - extra cellular

A

only records a few 100 neurons, may miss the right spot, may find diff result 1/2 mm over

doesn’t relate to the larger picture - only see small part

41
Q

in animal exp people are concerned about what processes involed

whats the big question

where do they draw the line

A

care and housing
surgical implants
training via deprivation
consent
suffering
killed after

is the gain to humanity worth the animal suffering
draw the line between a fly and a cat

42
Q

animal 1st and 2nd most commonly used for these tests

A

mice then fish then cattle - not neuroscience specific

primates used in science brain ones

43
Q

brain machine interfaces
show the gain of animal testing
how did the robot arm work

A

implact multi-electrode array into primary motor cortex of human,

connector on their skill reads data from neurons and passes it to computer to control robot arm

44
Q

in robot arm, how did they deocde motor cortex activity

A

asked patient to imagine moving arm forward - labeled that as forward movement

train computer program with these brain data and what movements they represent