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Turgeon 6th > 9 > Flashcards

9 Flashcards

1
Q
  1. Lymph nodes are
    A. primary lymphoid tissue
    B. secondary lymphoid tissue
    C. either primary or secondary tissue
    D. not a lymphoid tissue
A

B. secondary lymphoid tissue

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2
Q
  1. Liver is
    A. primary lymphoid tissue
    B. secondary lymphoid tissue
    C. either primary or secondary tissue
    D. not a lymphoid tissue
A

D. not a lymphoid tissue

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3
Q
  1. Spleen is
    A. primary lymphoid tissue
    B. secondary lymphoid tissue
    C. either primary or secondary tissue
    D. not a lymphoid tissue
A

B. secondary lymphoid tissue

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4
Q
  1. Red bone marrow is
    A. primary lymphoid tissue
    B. secondary lymphoid tissue
    C. either primary or secondary tissue
    D. not a lymphoid tissue
A

A. primary lymphoid tissue

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4
Q
  1. Thymus is
    A. primary lymphoid tissue
    B. secondary lymphoid tissue
    C. either primary or secondary tissue
    D. not a lymphoid tissue
A

A. primary lymphoid tissue

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5
Q
  1. Peyer’s patches of the intestine are
    A. primary lymphoid tissue
    B. secondary lymphoid tissue
    C. either primary or secondary tissue
    D. not a lymphoid tissue
A

B. secondary lymphoid tissue

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6
Q
  1. T cells are found in the
    A. perifollicular areas of the lymph nodes
    B. paracortex regions of the lymph nodes
    C. periarteriolar regions of the spleen
    D. all of the above
A

D. all of the above

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7
Q
  1. A major site of B-lymphocyte localization and proliferation is
    A. lymphoid follicles
    B. deep cortical zone
    C. paracortex
    D. all of the above
A

A. lymphoid follicles

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8
Q
  1. The process of lymphocyte recirculation is important in
    A. antibody production
    B. lymphocyte proliferation
    C. dissemination of antigen-sensitized memory cells
    D. commitment of lymphocytes to T and B cells
A

C. dissemination of antigen-sensitized memory cells

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9
Q
  1. T lymphocytes constitute _____% of the blood lymphocyte pool in adults.
    A. 0–20
    B. 20–40
    C. 40–60
    D. 60–85
A

D. 60–85

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10
Q
  1. Lymphocytes represent approximately _____% of the total circulating leukocytes in adults.
    A. 15
    B. 35
    C. 55
    D. 75
A

B. 35

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11
Q
  1. The percentage of lymphocytes as compared with the other types of leukocytes in the peripheral blood _____ as humans age.
    A. increases
    B. decreases
    C. remains the same
    D. is not predictable
A

B. decreases

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12
Q
  1. If an adult patient has a total leukocyte count of 20 × 109/L and a 50% lymphocyte count on the differential count, the absolute lymphocyte value is _____ × 109/L.
    A. 1
    B. 5
    C. 10
    D. 15
A

C. 10

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13
Q
  1. If an adult has a percentage of lymphocytes exceeding the normal reference range, this is called
    A. absolute lymphocytosis
    B. relative lymphocytosis
    C. leukocytosis
    D. leukopenia
A

B. relative lymphocytosis

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14
Q
  1. If an adult female has a total white blood cell count of 4.6 × 109/L and a leukocyte differential of segmented neutrophils 24%, eosinophils 4%, monocyte 8%, and lymphocytes 64%, she is demonstrating
    A. absolute lymphocytosis
    B. relative lymphocytosis
    C. leukopenia
    D. leukocytosis
A

B. relative lymphocytosis

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15
Q
  1. As a lymphocyte matures, the nuclear-cytoplasmic ratio
    A. increases
    B. decreases
    C. remains about the same
    D. is not predictable
A

A. increases

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16
Q
  1. As a lymphocyte matures, the overall size generally _________________ in older cells.
    A. increases
    B. decreases
    C. remains about the same
    D. is not predictable
A

B. decreases

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17
Q
  1. As a lymphocyte matures, the number of nucleoli
    A. increases
    B. decreases
    C. remains about the same
    D. is not predictable
A

B. decreases

18
Q
  1. As a lymphocyte matures, the chromatin clumping
    A. increases
    B. decreases
    C. remains about the same
    D. is not predictable
A

A. increases

19
Q
  1. As a lymphocyte matures, the quantity of cytoplasm
    A. increases
    B. decreases
    C. remains about the same
    D. is not predictable
A

B. decreases

20
Q
  1. The most characteristic morphological features of variant lymphocytes include

A. increased overall size, possibly one to three nucleoli, and abundant cytoplasm
B. increased overall size, round nucleus, and increased granulation in the cytoplasm
C. segmented nucleus, light-blue cytoplasm, and no nucleoli
D. enlarged nucleus, six to eight nucleoli, and dark-blue cytoplasm

A

A. increased overall size, possibly one to three nucleoli, and abundant cytoplasm

21
Q

Rieder’s cells are associated with
A. Niemann-Pick disease and Burkitt’s lymphoma
B. CLL
C. leukosarcoma
D. Natural artifact

22
Q

. Vacuolated lymphocytes are associated with

A. Niemann-Pick disease and Burkitt’s lymphoma
B. CLL
C. leukosarcoma
D. natural artifact

A

A. Niemann-Pick disease and Burkitt’s lymphoma

23
Q

Crystalline inclusions are associated with
A. drug toxicity
B. T-cell lymphoproliferative disorder
C. B-cell lymphoproliferative disorder
D. natural artifact

A

C. B-cell lymphoproliferative disorder

24
Q

Smudge cells are associated with
A. Niemann-Pick disease and Burkitt’s lymphoma
B. CLL
C. leukosarcoma
D. natural artifact

25
Q

Antibody production is associated with

A. granulocytes
B. lymphocytes
C. monocytes
D. macrophages

A

B. lymphocytes

26
Q

T cells are responsible for
A. humoral immunity
B. cell-mediated immunity
C. Growth and differentiation
D. all of the above

A

D. all of the above

27
Q

Functions of sensitized T lymphocytes include
A. protection against intracellular pathogens
B. chronic rejection in organ transplantation
C. production of immune antibodies
D. both A and B

A

D. both A and B

28
Q

A major function of CD4+ (Th2 subset) lymphocytes is
A. extracellular bacteria defense
B. phagocytosis
C. extracellular fungi defense

A

A. extracellular bacteria defense

29
Q

A patient with AIDS most likely has a decrease in
A. CD4+ cells
B. CD8+ cells
C. monocytes
D. macrophages

A

A. CD4+ cells

30
Q

The CD markers including CD4 and CD8 are associated with
A. NK cells
B. T lymphocytes
C. B lymphocytes
D. plasma cells

A

B. T lymphocytes

31
Q

The subset of B lymphocytes that can produce high levels of IL-10
is
A. CD21lo
B. B2 cells
C. B1
D. regulator B cells

A

D. regulator B cells

32
Q

Antibody-independent roles for B cells in immune responses include
A. production of antibody
B. production of cytokines to shape type and strength of immune response
C. blocking of cellular activation and recruitment of other immune cells
D. blocking of T-reg lymphocyte expansion

A

B. production of cytokines to shape type and strength of immune response

33
Q

The effect of IL-21 on B lymphocytes is
A. promoting differentiation of B cells to become plasma cells
B. stimulating B lymphocyte proliferation
C. promoting apoptosis
D. promoting stem cell production

A

A. promoting differentiation of B cells to become plasma cells

34
Q

One of the CD markers that distinguishes early-B cells from other maturational stages of B cell development is
A. CD4
B. CD3
C. CD10
D. CD56

35
Q

Lymphocyte development in the thymus and bursal equivalent are
A. antigen independent
B. antigen dependent
C. antibody independent
D. antibody dependent

A

A. antigen independent

36
Q

A characteristic feature of a early or immature B cell is
A. cytoplasmic (cIg) immunoglobulin chains
B. surface immunoglobulin (sIg) as IgM
C. surface immunoglobulin (sIg) as IgG
D. both A and B

A

D. both A and B

37
Q

The surface marker associated with B lymphocytes is
A. CD43+
B. CD19+
C. CD10+
D. IgM

38
Q

Mature B cell produces surface immunoglobulin (sIg)
A. IgM
B. IgD
C. IgA
D. both A and B

A

D. both A and B

39
Q

A phenotypic marker of a distinct subset of NK cells is
A. CD19
B. CD20
C. CD56bright
D. CD4

A

C. CD56bright

40
Q
  1. B lymphocytes
    A. are activated by antigen
    B. can secrete antibodies
    C. participate in cellular immunity response
    D. both A and B
A

D. both A and B

41
Q
  1. Plasma cells are

A. CD4+ T cells
B. CD8+ B cells
C. terminally (end stage) of differentiated B cells
D. end stage of differentiated T cells

A

C. terminally (end stage) of differentiated B cells

42
Q

Long-lived plasma cells are generated in

A. T-independent germinal centers
B. T-dependent germinal centers
C. B-independent germinal centers
D. B-dependent germinal centers

A

B. T-dependent germinal centers

43
Q

An abnormal plasma cell with red-staining cytoplasm is a
A. Russell’s body
B. Mott cell
C. grape cell
D. flame cell

A

D. flame cell

Turgeon 6th (32 decks)

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