13

Question 1

1. Acquired aplastic anemia may be caused by
   A. benzene or benzene derivatives
   B. ionizing radiation and vitamin B12
   C. purine or pyrimidine analogues
   D. all of the above

Answer 1

D. all of the above

Question 2

2. The sudden appearance of aplastic anemia or pure red cell aplasia is often caused by
   A. a hemolytic process
   B. an immune process
   C. acute leukemias
   D. chronic leukemias

Answer 2

B. an immune process

Question 3

3. Aplastic anemia can occur years before a diagnosis of _____ is made.
   A. paroxysmal nocturnal hemoglobinuria
   B. myelodysplasia
   C. acute myelogenous leukemia
   D. all of the above

Answer 3

D. all of the above

Question 4

4. If a patient with aplastic anemia is referred to as exhibiting pancytopenia, which cell lines are affected?
   A. Erythrocytes
   B. Leukocytes
   C. Thrombocytes
   D. All of the above

Answer 4

D. All of the above

Question 5

5. A characteristic of Fanconi’s anemia is
   A. a subset of Fanconi’s anemia
   B. a rare congenital form of red cell aplasia
   C. is characterized by selective failure of red blood cell production
   D. the best-described congenital form of aplastic anemia

Answer 5

D. the best-described congenital form of aplastic anemia

Question 6

6. A characteristic of familial aplastic anemia is
   A. a subset of Fanconi’s anemia
   B. a rare congenital form of red cell aplasia
   C. is characterized by selective failure of red blood cell production
   D. the best-described congenital form of aplastic anemia

Answer 6

A. a subset of Fanconi’s anemia

Question 7

7. A characteristic of pure red cell anemia is
   A. a subset of Fanconi’s anemia
   B. a rare congenital form of red cell aplasia
   C. is characterized by selective failure of red blood cell production
   D. the best-described congenital form of aplastic anemia

Answer 7

C. is characterized by selective failure of red blood cell production

Question 8

8. A characteristic of Diamond-Blackfan syndrome is
   A. a subset of Fanconi’s anemia
   B. a rare congenital form of red cell aplasia
   C. Is characterized by selective failure of red blood cell production
   D. the best-described congenital form of aplastic anemia

Answer 8

B. a rare congenital form of red cell aplasia

Question 9

9. Fanconi’s anemia is associated with abnormal genes located on chromosomes __q___, __q___.

A. 9, 20
B. 5, 22
C. 9, 12
D. 8, 23

Answer 9

A. 9, 20

Question 10

10. Acute (transient) red cell aplasia can be associated with
    A. a recent viral infection
    B. a bacterial infection
    C. a parasitic infection
    D. idiopathic causes

Answer 10

A. a recent viral infection

Question 11

11. Diamond-Blackfan anemia (DBA) is a
    A. microcytic, hypochromic anemia
    B. megaloblastic anemia
    C. congenital form of aplastic anemia
    D. white blood cell deficiency

Answer 11

C. congenital form of aplastic anemia

Question 12

Congenital amegakaryocytic thrombocytopenia is manifested
A. in infancy
B. at about 10 years of age
C. in adolescence
D. in adulthood

Answer 12

A. in infancy