7D - Third Line of Defence Flashcards
third line of defence
a subset of the immune system within
vertebrates
- composed of
the humoral and cell-mediated
responses
-create a specific
immune response and form immunological memory.
- aka adaptive immune
system or specific immune
response
immunological memory
ability of the immune system to quickly and aggressively combat a
previously encountered pathogen due to the presence of T and B
memory cells
T lymphocyte
- type of lymphocyte that plays an important role in cell-mediated immunity.
cytotoxic T cells, T memory cells, and T helper cells
How do APCs process and present antigens?
APCs engulf and digest pathogens via phagocytosis.
They display pathogenic antigens on MHC Class II markers.
APCs travel through the lymphatic system to lymph nodes, where they present antigens to T helper cells.
What happens after T helper cells recognize antigens?
Each T helper cell has unique receptors for a specific antigen.
When a T helper cell binds to its matching antigen, it becomes activated (or “selected”).
The activated T helper cell helps initiate the adaptive immune response (either humoral or cell-mediated).
antigen-presenting cell
subgroup of phagocytes that display the antigens from consumed pathogens on their surface and interact with the adaptive immune system
humoral immunity
an adaptive immune response in which
extracellular pathogens are targeted by specific antibodies produced by plasma cells. Also
known as B cell immunity
cell-mediated immunity
adaptive immune response in which infected or abnormal cells
are destroyed by cytotoxic T cells.
Also known as T cell immunity
T helper cell (Th)
a type of differentiated T lymphocyte that supports the functioning of a number of different immune cells, including the cloning and differentiation of selected T and
B cells
B lymphocyte
imp in humoral immunity
differentiates into plasma cells and B memory cells
