7B - First Line of Defence Flashcards
innate immune system
a component of the immune system that is composed of generalised and non-specific defences and/or responses to
pathogens. Also known as the non-specific immune system.
first line of defence
a component
of the innate immune system characterised by the presence of physical, chemical, and microbiological barriers to keep pathogens out of the host organism
second line of defence
component of the innate immune system characterised by the nonspecific response to injury and/or pathogens by a VARIETY OF CELLS AND MOLECULES
physical barrier
a component
of the first line of defence that
features solid or fluid obstacles that block pathogen entry such as
skin or mucus
chemical barrier
a component
of the first line of defence that features the use of enzymes, toxins, and acids to protect against
pathogen invasion
examples of physical defence in plants
Thick bark
* Waxy cuticles of leaves
* Formation of galls (abnormal outgrowth of tissues) to prevent the spread of infection
* Presence of thorns and trichomes (small hairs on plant surface) to deter insects and grazers
* Closing of stomata to prevent pathogen invasion during carbon
dioxide uptake
Chitinases –
enzymes that occur in a number of different plants and have antifungal properties
Oxalic acid –
a substance that can be toxic if ingested
- Phenols –
secreted by wounded plants, repelling or killing invading
microorganisms
microbiological barrier
component of the first line of defence in which the presence of normal flora limits the growth of
pathogenic bacteria. Also known as microbiota barrier
normal flora
microorganisms that are always present on or in a person and usually do not cause any disease.
examples of physical barriers for animals
Intact skin and surfaces between external and internal environments
* Mucous secretions and/or hairs in the respiratory tract that trap organisms, and
cilia that sweep them away from the airways and into the throat where they are
swallowed and destroyed by the gastrointestinal tract
chemical barriers in animals
lysozyme enzymes in tears and saliva that destroy bacterial cell walls
* Acidic sweat that destroys pathogens growing on the surface of the body
* Stomach acid that destroys pathogens that have been eaten /swallowed
* Antibacterial compounds in earwax
* Antibacterial proteins in semen
* Low pH in the vagina
microbiological defence in animals
Presence of bacteria on the skin, in the lower gastrointestinal tract, and the vagina