7/16 Questions Exam 1 Flashcards
What is the function of each type of bone cell?
Osteoblast form bone
Osteocytes maintain bone
Osteoclast remodel bone
What are the bone cells embedded in?
Amorphous matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
glycosaminoglycans
What types of glycosaminoglycans predominate in bone?
Chondroitin Sulfate
Keratin Sulfate
Hyaluronic Acid
What is the principal type of protein fiber in bone?
Collagen type 1
What is the most frequently described deposit in bone?
Hydroxyapatite
Bone is also the repository for what additional ions?
Sodium Magnesium Fluoride Lead Strontium Radium
What is Wolff’s law as it pertains to bone?
Living tissue will respond to stressors; bone is formed or absorbed in response to stress
What are the three responses of bone that allow it to be described as living?
It has the ability to heal
To remodel under stressors
And to age
What is bone the embryological derivative of?
Mesenchyme or Cartilage
What is the name given to the pattern of ossification in mesenchyme?
Intramembranous ossification
What is the timing for the appearance of intramembranous ossification?
From the second to third month in utero
What is the name given to the pattern of ossification in cartilage?
Endochondral ossification
What is the timing for the appearance of ossification in cartilage?
From the second to fifth month in utero
What part of the skull is derived from endochondral ossification?
Chondrocranium
Which skull bones are ossified by both endochondral and intramembranous ossification?
Mandible
Sphenoid
Temporal
Occipital
Which bone of the appendicular skeleton is formed by both endochondral and intramembranous ossification?
Clavicle
What are the names given to the centers of ossification based on time of appearance?
Primary centers of ossification appear before birth
Secondary centers of ossification appear after birth
What is the name given to the bone below an articulating surface?
Subchondral bone
What is the name of the outer fibro-cellular covering of bone?
Periosteum
What is the name given to the fibro-cellular lining of bone?
Endosteum
What are the four basic tissues of the human body?
Epithelial
Muscle
Neural
Connective