[68] Congenital Rubella Flashcards
What is congenital rubella syndrome?
A condition that can occur in the fetus of a pregnant woman who has contracted rubella, usually in the first trimester
What causes rubella?
Rubella virus
What does rubella cause in adults?
Usually a mild, self-limiting viral infection
how does fetal infection with rubella virus occur?
Transplacentally
What is the likely cause of the defects in congenital rubella syndrome?
Vasculitis resulting in tissue necrosis
What is the classic triad for congenital rubella syndrome?
- Sensorineural deafness
- Eye abnormalities
- Congenital heart disease
What eye abnormalities are common in congenital rubella syndrome?
- Retinopathy
- Cataracts
What congenital heart diseases are common with congenital rubella syndrome?
- Pulmonary artery stenosis
- PDA
What are the other potential manifestations of congenital rubella syndrome?
- Spleen, liver or bone marrow problems
- Intellectual disability
- Microcephaly
- Low birth weight
What can be used to detect rubella in a pregnant woman?
Detection of IgM in the saliva
What is the gold standard test for rubella?
PCR
What are the differentials for congenital rubella syndrome?
Other congenital infections
What is usually offered if IgM positive in first 16 weeks of pregnancy?
Termination of pregnancy
What is needed if parents continue with pregnancy?
Special educational provisions depending on the presence of handicaps
What can sometimes be helpful in treating hearing defects?
Cochlear implant
