[32] Cerebral Palsy Flashcards
What is cerebral palsy?
A chronic disorder or movement and/or posture that presents early and continues throughout life
When does cerebral palsy present?
Before 2 years old
What is cerebral palsy characterised by?
Abnormal muscle tone, reflexes, or motor development
What is the incidence of cerebral palsy?
It occurs in about 2.1 per 1000 live births
What are the sub-types of cerebral palsy classified on the basis of?
The specific problems present
What are the sub-types of cerebral palsy?
- Spastic cerebral palsy
- Ataxic cerebral palsy
- Athetoid cerebral palsy
What is spastic cerebral palsy?
Those with stiff muscles
What is ataxic cerebral palsy?
Those with poor co-ordination
What is athetoid cerebral palsy?
Those with writhing movement
Do the sub-types of cerebral palsy occur on their own or together?
Most children have a mixed disorder
What is the underlying mechanism of spastic cerebral palsy
Damage to the upper motor neurone (pyramidal or corticospinal tract) pathway
What is unilateral spastic cerebral palsy most commonly caused by?
Neonatal stroke
What is bilateral (quadriplegic) spastic cerebral palsy most commonly caused by?
Perinatal hypoxic-ischaemic encephalopathy
What is bilateral (diplegic) spastic cerebral palsy most commonly caused by?
Preterm birth, due to periventricular brain damage
What is the underlying mechanism of dyskinetic cerebral palsy?
Damage or dysfunction to the basal ganglia, or their associated pathway
What is dyskinetic cerebral palsy most commonly caused by?
Hypoxic-ischaemic encepahlopathy at term
What is the underlying mechanism of ataxic cerebral palsy?
Most cases are genetically determined
What is the underlying mechanism of cerebral palsy?
Caused by abnormal development or damage to parts of the brain that control movement, balance, and posture
When does damage to the brain causing cerebral palsy occur?
Most often, problems occur during pregnancy, however they may occur during childbirth or shortly after birth
What % of cases of cerebral palsy are thought to have an inherited genetic cause?
About 2%
Is there always an identifiable cause in cerebral palsy?
No
Give some typical causes of cerebral palsy?
- Problems with intra-uterine development
- Hypoxia of the brain
- Birth trauma during labour and delivery
- Complications around birth or during childhood
Give 3 examples of problems with intrauterine development that can cause cerebral palsy
- Exposure to radiation
- Infection
- Fetal growth restriction
Give 2 examples of causes of hypoxia to the brain that can cause cerebral palsy
- Thrombotic events
- Placental conditions
What are the risk factors for cerebral palsy?
- Pre-term birth
- Being a twin
- Certain infections during pregnancy, e.g. toxoplasmosis, rubella
- Exposure to methylmercury during pregnancy
- Difficult delivery
- Head trauma during first few years of life