6.1 QR cell cycle Flashcards
What is interphase? What stages does it consist of?
Growth period, G1, S, G2
What happens during interphase? 5 points
- DNA replicated + checked for errors
- Protein synthesis
- Mitochondria grow + divide
- In plants, chloroplasts grow + divide
- Normal metabolic processes of cell occur
What happens during G1?
1st growth phase: proteins from which organelles are made are produced + organelles replicate. Cell increases in size
What happens during S?
Synthesis: DNA is replicated in nucleus
What happens during G2?
2nd growth phase: Cell increases in size, energy stores increased, DNA checked for errors
What are the final 2 stages of the cell cycle? Define
them
Mitosis - nucleus divides
Cytokinesis - cytoplasm divides into 2 cells
What is the G0 phase?
When a cell temporarily/permanently leaves the cell
cycle
What are the 2 reasons for why a cell might leave the cell cycle?
- Differentiation - cell becomes specialised so never returns into cell cycle
- DNA is damaged and enters permanent cell arrest
(G0)
Explain the G1 checkpoint. What does it check for?
Checks for: cell size, nutrients, growth factors, DNA damage
If cell has errors, it enters G0 before S
What is checked at the G2 checkpoint?
Cell size, DNA replication, DNA damage
What does the spindle assembly checkpoint check for?
Chromosome attachment to spindles