4th Histology Lecture Exam - Skin, GIT, and Accessory Organs (Batch 2025) Flashcards
- The epidermis is lined by which type of epithelium?
A. Stratified columnar epithelium
B. Keratinized stratified squamous epithelium
C. Non-keratinized simple squamous epithelium
D. Simple columnar epithelium
Keratinized stratified squamous epithelium
Epidermis –
Epithelial Tissue Layer (*Stratified Squamous Keratinized ET); Ectodermal in origin.
Dermis – Connective Tissue Layer.
Papillary: Loose (Areolar) CT;
Reticular: Dense Irregular CT. *Both Fibrous.
Hypodermis/ Subcutaneous Tissue – Not part of the skin
Loose CT w/ Adipocytes
- This epidermal layer is seen only in palms and soles
A. Stratum spinosum
B. Stratum corneum
C. Stratum basale
D. Stratum lucidum
Stratum lucidum
CLG-SB (Thick Skin)
S. corneum: Dead Keratinocytes
S. lucidum: Dead Keratinocytes
S. granulosum: Keratohyaline (apoptosis)
S. spinosum: Langerhans/ Dendritic Cells (APC/Macrophage)
S. basale: Stem cells/Merkel cells/ Melanocytes
- This layer is composed of cuboidal cells
A. Stratum granulosum
B. Stratum corneum
C. Stratum basale
D. Stratum spinosum
Stratum basale
S. corneum: Flattened Squamous Keratinocytes
S. lucidum: - Flattened
Granular/ S. granulosum: Flattened
Spinous/ S. spinosum: Polyhedral cells w/ central nuclei
Basal/ S. basale : Cuboidal/ Columnar cells
- These epidermal cells are mechanoreceptors for light touch
A. Keratinocytes
B.Langerhan cells
C.Merkel cells
D.Melanocytes
Merkel cells
- This gland is dependent on sex hormones
A. Eccrine Sweat gland
B. Pacinian corpuscle
C. Apocrine sweat gland
D. Meissner corpuscle
Apocrine sweat gland
Dermal Appendages (Reticular Dermis)
Sweat Gland:
Simple Coiled Tubular: Eccrine (Merocrine), Apocrine
Sebaceous Glands:
Compound Acinar (Grape-like Structure)
Hair Follicle:
Dead Keratizined Epithelial Cell
- Mostly found in the perineum and axillary regions
A. Meissner corpuscle
B. Pacinian corpuscle
C. Apocrine sweat gland
D. Eccrine Sweat gland
Apocrine sweat gland
Location: Axilla, Areola, Perianal, Genital Area
- This sweat gland is most numerous on the soles
A. Eccrine Sweat gland
B. Pacinian corpuscle
C. Meissner corpuscle
D. Apocrine sweat gland
Eccrine Sweat gland
- Its outer capsule is made up of flattened Schwann cells
A. Apocrine sweat gland
B. Eccrine Sweat gland
C. Pacinian corpuscle
D. Meissner corpuscle
Pacinian corpuscle
Uncapsulated:
Merkel cells: each associated with expanded nerve
endings
Free nerve endings: in the papillary dermis and extending into lower epidermal layers
Root hair plexuses: a web of sensory ibers surrounding the bases of hair follicles in the reticular dermis that detects movements of the hairs.
Encapsulated
Meissner corpuscles are elliptical structures, 30-75
μm by 50-150 μm, consisting of sensory axons winding
among lattened Schwann cells arranged perpendicular
to the epidermis in the dermal papillae
Lamellated (pacinian) corpuscles are large oval struc-
tures, approximately 0.5 mm by 1 mm, found deep in the
reticular dermis and hypodermis, with an outer capsule
and 15-50 thin, concentric lamellae of lattened Schwann
cells and collagen surrounding a highly branched, unmy-
elinated axon .
Krause end bulbs are simpler encapsulated, ovoid
structures, with extremely thin, collagenous capsules
penetrated by a sensory iber.
Ruffini corpuscles have collagenous, fusiform capsules
anchored irmly to the surrounding connective tissue
- Receptor for low frequency vibration
A. Meissner corpuscle
B. Apocrine sweat gland
C. Pacinian corpuscle
D. Eccrine Sweat gland
Meissner corpuscle
- This structure has adrenergic innervation
A. Apocrine sweat gland
B. Eccrine Sweat gland
C. Meissner corpuscle
D. Pacinian corpuscle
Apocrine sweat gland
Sweat Gland:
Eccrine (Merocrine) Sweat Gland
-Release sweat to adjust body temperature (**Exocytosis)
Apocrine Sweat Gland
-Respond to stress and sexual stimulation (*Release on hair follicle).
-Influenced by hormones; Seen in axilla, areola, perianal and genital area.
-Contains fatty acids (That gives distinctive body odor).
- Which layer of the epidermis contains keratohyaline granules?
A. Stratum corneum
B. Stratum spinosum
C. Stratum granulosum
D. Stratum corneum
Stratum granulosum
S. corneum: Dead Keratinocytes
S. lucidum: Dead Keratinocytes
S. granulosum: Keratohyaline (apoptosis)
S. spinosum: Langerhans/ Dendritic Cells (APC/Macrophage)
S. basale: Stem cells/Merkel cells/ Melanocytes
- Which of the following cells are antigen presenting cells found in the skin?
A. Pacinian corpuscle
B. Merkel cells
C. Kupffer cells
D. Langerhan cells
Langerhan cells
S. corneum: Dead Keratinocytes
S. lucidum: Dead Keratinocytes
S. granulosum: Keratohyaline (apoptosis)
S. spinosum: Langerhans/ Dendritic Cells (APC/Macrophage)
S. basale: Stem cells/Merkel cells/ Melanocytes
- A new skin product is said to boost collagen production. Which of the cells is its target?
A. Merkel cells
B. Keratinocyte
C. Melanocyte
D. Fibroblast
Fibroblast
Fibroblast:
-Produces Collagen and Elastic Fibers
- Which is the growing part of the nail?
A. Matrix
B. Root
C. Nail bed
D. Lunula
Matrix
- Which of the following is the most abundant receptor of the skin
A. Pacinian corpuscles
B. Ruffini’s corpuscle
C. Free nerve endings
D. Krause’s end bulb
Free nerve endings
- Where is thick skin found?
A. Palms
B. Back
C. Knees
D. Nape
Palms
- It is a thin layer composed of loose connective tissue
A. None
B. Both
C. Papillary layer of the dermis
D. Reticular layer of the dermis
Papillary layer of the dermis
- Responsible for the elasticity of the skin
A. Both
B. None
C. Reticular layer of the dermis
D. Papillary layer of the dermis
Reticular layer of the dermis
- Contains fibroblasts, mast cells and leukocytes
A. Reticular layer of the dermis
B. None
C. Papillary layer of the dermis
D. Reticular layer of the dermis
Papillary layer of the dermis
- Contains numerous keratinocytes
A. Papillary layer of the dermis
B. Both
C. None
D. Reticular layer of the dermis
None
- This is the outermost epithelial cell layer without nuclei or organelles
A. Stratum lucidum
B. Stratum corneum
C. Stratum granulosum
D. Stratum basale
Stratum corneum
- This epidermal cell is responsible for skin pigmentation
A. Melanocyte
B. Keratinocyte
C. Merkel cell
D. Langerhan cell
Melanocyte
- Which cell is found on the dermis?
A. Fibroblast
B. Melanocyte
C. Keratinocyte
D. Collagen
Fibroblast
- Which of the following responds to pain?
A. Free nerve endings
B. Ruffini’s corpuscle
C. Krause’s end bulbs
D. Meissner’s corpuscle
Free nerve endings
- What is the correct term of cuticle?
A. Eponychium
B. Root
C. Lunula
D. Nail bed
Eponychium
- Which is not considered as an epidermal appendage?
A. Nail
B. Hair
C. Hypodermis
D. Sebaceous gland
Hypodermis
Epidermal appendage
Sweat Gland, Sebacceous Gland, Hair Follicle, Nails
- This epidermal layer is composed of numerous cell layers which appears pointy
A. Stratum spinosum
B. Stratum basale
C. Stratum germinativum
D. Stratum lucidum
Stratum spinosum
- Layers of the Epidermis:
THICK SKIN (Top to bottom)
S. corneum, S. lucidum, S. granulosum, S. spinosum, S. basale.
- Which layer is on the surface of the skin?
A. Stratum spinosum
B. Stratum lucidum
C. Stratum basale
D. Stratum corneum
Stratum corneum
- Layers of the Epidermis:
THICK SKIN (Top to bottom)
S. corneum, S. lucidum, S. granulosum, S. spinosum, S. basale/germinativum
- What type of glands are the glands of Moll?
A. Apocrine sweat gland
B. Endocrine gland
C. Eccrine sweat gland
D. Sebaceous gland
Apocrine sweat gland
The ciliary glands (glands of Moll) are modified apocrine sweat glands that are found on the margin of the eyelid.
They are next to the base of the eyelashes, and anterior to the Meibomian glands within the distal eyelid margin. These glands are relatively large and tubular-shaped, and secrete lipid that adds to the superficial layer of the tear film, retarding evaporation.
- Which is the receptor of fine touch?
A. Free nerve endings
B. Ruffini’s corpuscle
C. Meissner’s corpuscle
D. Krause’s end bulbs
Meissner’s corpuscle
Receptors
Merkel’s cells: light touch
Meissner corpuscle: low frequency vibration/ fine touch
Free nerve endings: pain
- Which of the following statements regarding the esophagus is correct?
A. Lined with non-keratinized simple squamous epithelium
B. It is entirely covered with adventitia
C. Distal 1/3 is made up of skeletal muscle
D. Mucus secreting glands are found in the lamina propia and submucosa
Mucus secreting glands are found in the lamina propia and submucosa
Submucosa:
o Dense Irregular Collagenous Tissue; Blood Vessels, Nerves, Lymphatic Vessels.
o Meissner’s Plexuses (Submucosal Nerve Plexuses) – Function: Secretion.
o Deep Esophageal Glands (Esophageal Glands Proper).
- Which one is specific for duodenum?
A. Brunner’s gland
B. Intestinal gland
C. Crypts of Lieberkuhn
D. Lacteals
Brunner’s gland
- What do you call the **neuroendocrine cells **found at the lamina propia of the GIT?
A. Argentaffin cells
B. Kulchitsky cells
C. Paneth cells
D. Goblet cells
Argentaffin cells
Enteroendocrine (Endrocrine, Argentaffin) Cells – Scattered epithelial cells in the gastric mucosa with endocrine or paracrine functions.
* In Fundus – Secretes: Serotonin – Inhibits gastric acid secretion, stimulates production and release of gastric mucus.
* In Pylorus (Antrum) – Produces: Gastrin (G-Cell) – Stimulates secretion of acid and pepsinogen.
- Gastrin is produced in which of the following?
A. Body
B. Fundus
C. Antrum
D. Pylorus
Antrum
Enteroendocrine (Endrocrine, Argentaffin) Cells – Scattered epithelial cells in the gastric mucosa with endocrine or paracrine functions.
* In Fundus – Secretes: Serotonin – Inhibits gastric acid secretion, stimulates production and release of gastric mucus.
* In Pylorus (Antrum) – Produces: Gastrin (G-Cell) – Stimulates secretion of acid and pepsinogen.
- Which cell types is most prevalent within the gastric pit of the stomach?
A. Mucus secreting cells
B. Parietal cells
C. Columnar absortive cells
D. Paneth cells
Mucus secreting cells
- Hyperacidity of the stomach is due to hypersecretion of which cell?
A. Mucous neck cell
B. Columnar cell
C. Parietal cell
D. Zymogenic cell
Parietal cell
- Which of these cells will manifest Pernicious anemia if destroyed?
A. Absorptive cells
B. Paneth cells
C. Parietal cells
D. Goblet cells
Parietal cells
- In the GIT, the cells that secrete antibacterial enzymes are found in which of the following?
A. Crypts of Lieberkuhn
B. Lamina propia
C. Payer’s patch
D. Intestinal villi
Crypts of Lieberkuhn
- Plica circularis is a feature of which of the following?
A. Esophagus
B. Stomach
C. Small intestine
D. Large intestine
Small intestine
- Which of the following would result to a reduced number of Paneth cells?
A. Decreased mucus secretion
B. Increased intestinal fats
C. Reduced sugar breakdown
D. Increased intestinal bacteria
Increased intestinal bacteria