43 - Esclerose Sistémica (Esclerodermia) e Doenças Relacionadas Flashcards
1
Q
Auto-Acs na esclerose sistémica?
A
Autoantibodies unique to SSc, in particular:
- anti-centromere,
- anti-topoisomerase I, and
- anti-RNA polymerase III,
are useful for diagnostic and prognostic purposes. These three autoantibodies bind tissues of interest in SSc, as do anti-U3RNP (antifibrillarin), anti-Th/To, anti-U1RNP, anti-PM-Scl, and anti-Ku autoantibodies. The latter are rather rare and play a role in overlap syndromes.
