112 - Neoplasias Melanocíticas Benignas

Question 1

Complexo de Carney?

Answer 1

The Carney complex is an autosomal dominant syndrome characterized by:
- multiple lentigines;
- multiple neoplasias, including: myxomas of the skin, heart (atrial), and breast;
- psammomatous melanotic schwannomas;
- epithelioid blue nevi of skin and mucosae;
- growth hormone-producing pituitary adenomas;
- testicular Sertoli cell tumors.
Components of the Carney complex have been described previously as the NAME (nevi, atrial myxoma, myxoid neurofibroma, ephelides) and LAMB (lentigines, atrial myxoma, mucocutaneous myxoma, blue nevi) syndromes.

Question 2

Lentigo simplex?

Answer 2

Key feature:
Mácula castanha de aparecimento em idade precoce (vs lêntigo solar), com pouca ou nenhuma relação a exposição solar.