Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

SuprIM > 365 Gout and Other Crystal-Associated Arthropathies > Flashcards

365 Gout and Other Crystal-Associated Arthropathies Flashcards

Focus on gout

1
Q

Most common early clinical manifestation of gout (H20 C365 P2632)

A

Acute arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Polarized microscopy findings of synovial fluid in gout (H20 C365 P2632)

A

Needle-shaped MSU crystals that are brightly birefringent with negative elongation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Synovial fluid leukocyte counts in gout (H20 C365 P2632)

A

2,000-60,000/uL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Excretion of this amount of uric acud per 24 h on a regular diet suggests overproduction of purine (H20 C365 P2632)

A

> 800 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ultrasound finding in gout (H20 C365 P2632)

A

Double contour sign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Therapy for acute gout when NSAIDs, colchicine, and glucocorticoids have failed (H20 C365 P2633)

A

Daily anakinra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Serum uric acid target during probenecid or allopurinol therapy for gout (H20 C365 P2633)

A

<6 mg/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

This serum uric acid level is an indication to start hypouricemic therapy (H20 C365 P2633)

A

> 535 umol/L (>9 mg/dL)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Uricosuric drugs are indicated for patients with 24 hr excretion if uric acid of: (H20 C365 P2633)

A

<600 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Uricosuric drug that is more effective in patients with CKD (H20 C365 P2633)

A

Benzbromarone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Uricosuric agent approved only in patients already on a xanthine oxidase inhibitor (H20 C365 P2633)

A

Lesinurad

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The best drug to lower serum urate in patients with renal disease (H20 C365 P2633)

A

Allopurinol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The best drug to lower serum urate in urate stone formers (H20 C365 P2633)

A

Allopurinol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Toxicity with allopurinol has been recognized increasingly in patients taking these drugs (H20 C365 P2633)

A

Thiazide diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Toxicity with allopurinol has been recognized increasingly in patients allergic to: [2] (H20 C365 P2633)

A

Penicillin, ampicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pegylated uricase used in the treatment of gout (H20 C365 P2633)

A

Pegloticase

17
Q

Duration of colchicine anti-inflammatory prophylaxis in gout (H20 C365 P2633)

A

Until the patient is normouricemic and without gouty attacks for 6 months or as long as tophi are present

18
Q

Toxicity with allopurinol has been recognized increasingly in Asians expressing: (H20 C365 P2733)

A

HLA-B*58:01

SuprIM (31 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions