147 Tetanus Flashcards

1
Q

Maternal tetanus is defined as tetanus occurring during pregnancy or up to how long after pregnancy? (H20 C147 P1102)

A

6 weeks

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2
Q

Most common infection sites of tetanus in adults (H20 C147 P1102)

A

Superficial abrasions to the limbs

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3
Q

Persons of this age are at greatest risk of tetanus (H20 C147 P1102)

A

> 60 years

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4
Q

Tetanospasmin light chains cleaves this protein (H20 C147 P1103)

A

Synaptobrevin

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5
Q

Time from wound to first symptom of tetanus (H20 C147 P1103)

A

Incubation period

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6
Q

Time from first symptom to first generalized spasm in tetanus (H20 C147 P1103-4)

A

Period of onset

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7
Q

Most common cause of death in tetanus (H20 C147 P1104)

A

Respiratory failure

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8
Q

Major risk during the second week of severe tetanus (H20 C147 P1104)

A

Death due to cardiovascular events

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9
Q

Serum anti-tetanus IgG levels that are deemed supportive and do not support the diagnosis of tetanus (H20 C147 P1104)

A

> 0.1 IU/mL

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10
Q

Character of abdominal pain in teranus that differentiates it from strychnine poisoning and dystonic reaction to antidopaminergic drugs (H20 C147 P1104)

A

Continuous

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11
Q

Preferred antibiotic therapy for tetanus (H20 C147 P1104)

A

Metronidazole

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12
Q

Dose of human TIG for treatment of tetanus (H20 C147 P1104)

A

3000-5000 IU

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13
Q

Dose of equine-derived TIG in the treatment of tetanus (H20 C147 P1104)

A

10,000-20,000 IU

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14
Q

Dose of intrathecal TIG (H20 C147 P1104)

A

50-1,500 IU

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15
Q

Magnesium sulfate as sedative for tetanus is titrated to: [2] (H20 C147 P1104)

A

Plasma concentration 2-4 mmol/L, or against disappearance of patellar reflex

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16
Q

Primary method of maternal and neonatal tetanus elimination (H20 C147 P1105)

A

Immunization of pregnant women