147 Tetanus Flashcards
Maternal tetanus is defined as tetanus occurring during pregnancy or up to how long after pregnancy? (H20 C147 P1102)
6 weeks
Most common infection sites of tetanus in adults (H20 C147 P1102)
Superficial abrasions to the limbs
Persons of this age are at greatest risk of tetanus (H20 C147 P1102)
> 60 years
Tetanospasmin light chains cleaves this protein (H20 C147 P1103)
Synaptobrevin
Time from wound to first symptom of tetanus (H20 C147 P1103)
Incubation period
Time from first symptom to first generalized spasm in tetanus (H20 C147 P1103-4)
Period of onset
Most common cause of death in tetanus (H20 C147 P1104)
Respiratory failure
Major risk during the second week of severe tetanus (H20 C147 P1104)
Death due to cardiovascular events
Serum anti-tetanus IgG levels that are deemed supportive and do not support the diagnosis of tetanus (H20 C147 P1104)
> 0.1 IU/mL
Character of abdominal pain in teranus that differentiates it from strychnine poisoning and dystonic reaction to antidopaminergic drugs (H20 C147 P1104)
Continuous
Preferred antibiotic therapy for tetanus (H20 C147 P1104)
Metronidazole
Dose of human TIG for treatment of tetanus (H20 C147 P1104)
3000-5000 IU
Dose of equine-derived TIG in the treatment of tetanus (H20 C147 P1104)
10,000-20,000 IU
Dose of intrathecal TIG (H20 C147 P1104)
50-1,500 IU
Magnesium sulfate as sedative for tetanus is titrated to: [2] (H20 C147 P1104)
Plasma concentration 2-4 mmol/L, or against disappearance of patellar reflex