Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

SuprIM > 104 Non-Hodgkin Lymphoma > Flashcards

104 Non-Hodgkin Lymphoma Flashcards

1
Q

This specific subtype of NHL has a striking geographic occurrence, being most frequent in South Asia and parts of Latin America (H20 C104 P770)

A

Angiocentric nasal T/NK cell lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lymphoid malignancy associated with HTLV-1 infection (H20 C104 P771)

A

Adult T cell leukemia/lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Lymphoid malignancy associated with HCV infection (H20 C104 P771)

A

Lymphoplasmacytic lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Infectious agent associated with Burkitt lymphoma, post–organ transplant lymphoma, primary CNS diffuse large B-cell lymphoma, Hodgkin lymphoma, and nasal type extranodal NK/T-cell lymphoma (H20 C104 P771)

A

Epstein-Barr virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Infectious agent associated with diffuse large B-cell lymphoma and Burkitt lymphoma (H20 C104 P771)

A

HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Infectious agent associated with gastric MALT lymphoma (H20 C104 P771)

A

Helicobacter pylori

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Infectious agent associated with MALT lymphoma of the skin (H20 C104 P771)

A

Borrelia sp.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Infectious agent associated with MALT lymphoma of the conjunctiva (H20 C104 P777)

A

Chlamydophila psittaci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Infectious agent associated with small intestine MALT lymphoma (H20 C104 P771)

A

Campylobacter jejuni

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Infectious agent associated with primary effusion lymphoma and multicentric Castleman disease (H20 C104 P771)

A

Human herpesvirus 8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Type of NHL that is most frequently associated with immunosuppresion and autoimmune disease (H20 C104 P771)

A

DLBCLs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The master B lineage transciption factor (H20 C104 P771)

A

PAX5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T-cell master regulatory transciption factor (H20 C104 P771)

A

NOTCH-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Imaging test of choice in assessing lymphadenopathy for aggressive lymphomas (H20 C104 P773)

A

FDG PET

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

End-of-treatment FDG PET should preferably be done how many weeks after chemotherapy (H20 C104 P773)

A

6-8 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

End-of-treatment FDG PET should preferably be done how many weeks after radiation or radiochemotherapy (H20 C104 P773)

A

8-12 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Best predictor of outcome for NHL (H20 C104 P774)

A

International Prognostic Index

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Independent prognostic variable that is included in follicular lymphoma prognostic index but is not included in the IPI (H20 C104 P774)

A

Hemoglobin <12

19
Q

Second most common NHL and most common indolent NHL (H20 C104 P774)

A

Follicular lymphoma

20
Q

All of the intensive combination chemotherapy regimens for Burkitt’s lymphoma involve this drug (H20 C104 P775)

A

Cyclophosphamide

21
Q

Most common histologic subtype of NHL (H20 C104 P775)

A

Diffuse large B-cell lymphoma

22
Q

Standard first-line chemotherapy for DLBCL (H20 C104 P775)

A

R-CHOP

23
Q

New agent for relapsed DLBCL, particularly in the ABC cell of origin (H20 C104 P776)

A

Ibrutinib

24
Q

Treatment for relapsed/refractory DLBCL following two prior systemic therapies (H20 C104 P776)

A

Anti-CD19 CAR-T cells

25
Q

> 85% of patients with FL will harbor t(14;18) and overexpress this protein: (H20 C104 P776)

A

BCL2

26
Q

No. of centroblasts in grade II FL (H20 C104 P776)

A

6-15 centroblasts/hpf

27
Q

This grade of FL is an aggressive disease and is treated like DLBCL (H20 C104 P776-7)

A

Grade IIIb FL

28
Q

Best predictor of outcome in FL (H20 C104 P776)

A

FLIPI

29
Q

Standard of care for the first line therapy of medium to high volume follicular lymphoma (H20 C104 P777)

A

Bendamustine + Rituximab (BR)

30
Q

This treatment for FL is associated with considerable treatment-related morbidity so is usually reserved for patients with multiply relapsed FL that is no longer responsive to chemotherapy. (H20 C104 P777)

A

Allogeneic HSCT

31
Q

Rate of transformation of FL to DLBCL (H20 C104 P777)

A

~3% per year

32
Q

Aside from rituximab, this treatment for splenic MZL is reasonable for selected patients with excellent relief of symptoms and cytopenias (H20 C104 P777)

A

Splenectomy

33
Q

Most common cytogenetic abnormality in MALT lymphoma (H20 C104 P777)

A

t(14;18)

34
Q

Lymphoplasmacytic lymphoma with high levels of circulating IgM paraproteins (H20 C104 P777)

A

Waldenstrom macrogobulinemia

35
Q

Variant of mantle cell lymphoma that is more indolent (H20 C104 P778)

A

SOX11 variant

36
Q

Variant of mantle cell lymphoma that is associated with a poor prognosis (H20 C104 P778)

A

Blastic variant

37
Q

Pathognomonic cytogenetic findings in mantle cell lymphoma (H20 C104 P778)

A

t(11;14)

38
Q

Mycoisi fungoides associated with generalized erythroderma and circulating tumor cells (H20 C104 P778)

A

Sézary syndrome

39
Q

Histologic finding in anaplastic large cell lymphoma (H20 C104 P779)

A

Hallmark cells

40
Q

Conjugated anti-CD30 antibody to monomethly aurostatin E used to treat ALCL patients with chemosensitive disease or for ALK-negative disease (H20 C104 P779)

A

Brentuximab

41
Q

This type of lymphoma can be prevented with a gluten-free diet (H20 C104 P779)

A

Type I enteropathy-type intestinal T-cell lymphoma

42
Q

Adult T-cell leukemia/lymphoma is more prevalent in these regions [2] of the world (H20 C104 P779)

A

Japan, Caribbean basin

43
Q

Most common vairant of ATLL (H20 C104 P779)

A

Acute variant

44
Q

Pathognomonic histologic finding in adult T-cell leukemia/lymphoma (H20 C104 P779)

A

Flower cell

SuprIM (31 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions