3.2.3 Autoimmune Conditions Flashcards
How can radio contrast ellicit an immune response?
Direct activation of Mast cells
What is important to note about this image?
This image is pretty messed up, but notice the blue on the right side. BLUE=BAD
What type of necrosis is this?
Fibrinoid necrosis
What is this image associated with?
Vasculatis possibly polyarteritis nodosa
What are these images associated with?
Scleroderma
What is the important anti-body associated with scleroderma?
Anti-Scl-70
What is important about this image and what disease can it be associated with?
Dermis is very fibrous, there is an almost absence of normal hair follicles and sweat glands, and the above epidermis is flat with no saw tooth pattern.
The is epithelium associated with scleroderma
What is important about this image?
This is a medium sized arteriole in the kidney that has concentric intimal and medial fibrosis. “Onion skin”. Vascular lesions can lead to renal fibrosis and atrophy.
What are the antigens for SLE?
DNA, RNA, and native DNA
What is the important antibody associated with systemic sclerosis syndrome (Scleroderma)?
Scl-70 which targets DNA topoisomerase
What is the important antibody associated with Sjorgren Syndrome?
SS-A (Ro) or SS-B (La) targeting RNP
What is a possible drug to increase blood flow to the fingers?
Viagra
What is important about this image?
It is crescent-shaped characteristic of rapid progressing glomular nephritis or Crescentic glomerulonephritis
What is the Gell and Coombs classification for RPGN?
Type II hypersensitivity
What is the Gell and Coombs classification for Lupus?
Type III hypersensitivity
