3/27&28 psych Flashcards
cofactor for glutamate & GABA transaminase?
B6
fexofenadine
-what is it?
2nd gen. H1 blocker
2nd get H1 blockers
- suffix?
- exception?
- adine
- cetirizine
cetirizine
-what is it?
2nd get H1 blocker
-zertec
promethazine
-what is it?
1st gen H1 blocker
Buspirone
-pros?
Does not cause sedation, addiction, or tolerance.
DOPA
-short for what?
dihydroxyphenylalanine
rate-limiting step in catecholamine synth
tyrosine hydroxylase
-tyrosine => DOPA
reserpine
- mech:
- use:
-inhibits dopamine entry into pre-synaptic vesicles,
effectively causing a chemical sympathectomy.
-reduces BP & HR.
Ciliary muscle under what control?
Mostly muscarinic control.
-slight beta-2 control.
Opioids depress respiration by reducing responsiveness of central respiratory centers to ____
CO2
Highest risk age-group for suicide:
45-64
reuptake of Ca back into SR
-ATP dep?
yes, its ATP dependent. (ryanodine receptors).
- this is crucial part of malignant hyperthermia, burning all that ATP generates heat!
- high temp will induce muscle damage.
malignant hyperthermia
-how is the muscle damaged?
- low ATP & high temp from burning so much ATP damages muscle cells.
- you burn a lot of ATP trying to put that Ca back into the SR w/ryanodine receptors.
trigeminal neuralgia
-Tx:
carbamazepine
reduction of portal venous pressure to prevent variceal bleed
propranolol
Most feared side effect of carbamazepine
agranulocytosis
If a 3 year old doesn’t play cooperatively w/other, is that a social development delay?
No. At 3 yo children are expected to play in parallel w/other kids, not cooperatively.
phenelzine
-what is it?
MAO inhibitor
Depressed pt who has hypertensive crisis after a wine/cheese party.
MAO-inhibitor / tyramine crisis.
Classic conditioning v Operant conditioning
-which one is dealing w/involuntary responses & which w/voluntary?
classic = involuntary (ie. salivating). operant = voluntary (ie. behavior training).
Operant conditioning:
-what is “extinction”?
- Discontinuation of reinforcement (positive or negative) eventually eliminates behavior.
- ie. a child who climbs under his desk, a response which has been reinforced by attention, is subsequently ignored until the attention-seeking behavior no longer occurs.
Transference
-define:
Patient projects feelings about formative or other important persons onto physician (e.g., psychiatrist is seen as parent).
Countertransference
-define:
-Doctor projects feelings about formative or other important persons onto patient (e.g., patient reminds physician of younger sibling).
Dissociation
- mature or immature ego defense?
- define:
-immature
-Temporary, drastic change in personality, memory, consciousness, or motor behavior to avoid emotional stress.
-Extreme forms can result in dissociative identity
disorder (multiple personality disorder).
Denial
-mature or immature ego defense?
immature
Ego defenses
-conscious or unconscious?
unconscious
Displacement
- mature or immature ego defense?
- define:
- example:
-immature
-transfer of an impulse toward a safer & less
distressful object.
-husband yelling at his dog after argument w/wife.
Fixation
- mature or immature ego defense?
- define:
- example:
-immature
-Partially remaining at a more childish level of
development (vs. regression).
-Men fixating on sports games.
Identification
-mature or immature ego defense?
immature
Isolation
- mature or immature ego defense?
- define:
- example:
- immature
- Separating feelings from ideas and events.
- Describing murder in graphic detail with no emotional response.
Fantasy
-mature or immature ego defense?
immature
Projection
- mature or immature ego defense?
- define:
- example:
-immature
-projecting your “unacceptable” feelings onto someone
else.
-A man who wants another woman thinks his wife is cheating on him.
Rationalization
-mature or immature ego defense?
immature
Regression
- mature or immature ego defense?
- example:
-immature
-bedwetting in a previously toilet-trained child
when hospitalized
Repression
- mature or immature ego defense?
- voluntary or involuntary?
immature
-involuntary
Splitting
- mature or immature ego defense?
- commonly seen in which disorder?
- immature
- Commonly seen in borderline personality disorder.
Altruism
-mature or immature ego defense?
mature
Humor
-mature or immature ego defense?
mature
Sublimation
- mature or immature ego defense?
- define:
- example:
- mature
- Replacing an unacceptable wish with a course of action that is similar to the wish but does not conflict with one’s value system (vs. rxn formation).
- Teenager’s aggression toward his father is redirected to perform well in sports.
Reaction formation
- mature or immature ego defense?
- define:
- example:
-immature
-a person does the opposite of what he/she desires.
Usually a short-term immature response that eventually
breaks down. You feel bad about this desire.
-a former smoker vigorously enforcing a smoking ban.
Suppression
-mature or immature ego defense?
mature
mature ego defenses
-mnemonic:
Mature adults wear a SASH:
-Sublimation, Altruism, Suppression, Humor.
Anaclitic depression
- what is it?
- what is it a result of?
- infant withdrawn/unresponsive.
- result of infant deprivation.
Infant deprivation
- after how long are changes irreversible?
- what can severe deprivation result in?
> 6 mo
-Severe deprivation can result in infant death.
Sexual abuse of child
- peak age range?
- abuser?
- 9-12
- Known to victim, usually male
Physical abuse of child
- peak age range?
- abuser?
< 3 yo
-Usually biological mother
ADHD
- onset before age __
- intelligence level?
- associated w/what physical brain abnormality?
- 12
- normal intelligence but commonly coexists w/difficulties in school.
- Associated with frontal lobe volume/metabolism.
atomoxetine
- what is it?
- whats it used for?
- NE reuptake inhibitor.
- ADHD
Conduct disorder
- age range?
- will most likely progress to what?
- < 18yo
- After age 18, many of these patients will meet criteria for diagnosis of antisocial personality disorder.
Oppositional defiant disorder
-define:
Enduring pattern of hostile, defiant behavior toward authority figures in the absence of serious violations of social norms.
Tourette syndrome
- onset of age:
- how long must it last for a Dx?
- Tx:
- < 18 yo
- > 1 year
- antipsychotics and behavioral therapy.
Separation anxiety disorder
- common age of onset?
- Tx:
- 7-9 yrs
- SSRIs and relaxation techniques/behavioral interventions.
Pervasive developmental disorders
- define:
- name 2 of them:
- Delays in the development of socialization and communication skills.
- Autism spectrum disorder, Rette disorder.
Do autistic children get separation anxiety?
-no separation anxiety b/c there was no attachment
in the first place.
Rett disorder
- inheritance pattern:
- seen in which pt population:
- X-linked recessive
- Seen in GIRLS bc boys w/disease die in utero.
Rett disorder
-Sxs:
-loss of development, loss of verbal abilities, intellectual disability, ataxia, and stereotyped hand-wringing.
Anxiety: NT levels
- NE:
- 5-HT:
- GABA:
- inc. NE
- dec. GABA
- dec. 5-HT
Huntingtons disease: NT levels
- GABA:
- ACh:
- dopamine:
- dec. GABA
- dec. ACh
- inc. dopamine
Parkinson disease: NT levels
- dopamine:
- ACh:
- 5-HT:
- dec. dopamine
- inc. ACh
- inc. serotonin
Parkinsons disease
-serotonin level?
-inc. serotonin
Schizophrenia
-which NT level is off the most?
inc. dopamine
Orientation
-what 3 things do they check and in which order are they lost?
Order of loss:
1st—time
2nd—place
last—person.
Dissociative amnesia
-what is it?
Inability to recall important personal information, usually subsequent to severe trauma or stress.
-May be accompanied by dissociative fugue.
Dissociative fugue
Abrupt travel or wandering during a period of
dissociative amnesia, associated with traumatic circumstances.
Cognitive disorder
- define:
- what two syndromes does are encompassed?
- Significant change in cognition: memory, attention, language, judgment.
- Includes delirium and dementia.
“Waxing and waning” level of consciousness
with acute onset.
-delirium or dementia?
Delirium
Delirium vs Dementia
- onset:
- consciousness:
- course:
- Delirium = acute = impaired consciousness = fluctuating
- Dementia = gradual (months to years) = intact consciousness = progressive
Delirium vs Dementia
-reversible?
Delirium = reversible Dementia = irreversible
Delirium
-check drugs for which type of effect?
-anticholinergic effects.
Delirium
- hallucinations?
- if so what type?
hallucinations = often visual.