21 Exercise respiration and CEST Flashcards
0
Q
RQ
A
Respiratory quotient- ratio of CO2 production to O2 consumption at tissue level
1
Q
Change in breathing with exercise
A
Low intensity increases tidal volume
Higher intensity increases rate
- pO2 generally unchanged
- at 60% maximal effort pH lowers 2/2 lactic acid
- pCO2 decreses (hyperventolation)
- DLCO increases 2/2 increased alveolar recruitment
2
Q
RER
A
Respiratory exchange rate- RQ (ratio of CO2 production to O2 consumption) at atmospheric level
3
Q
pH of exercising muscle
A
7
4
Q
Anaerobic threshold
A
- Level of O2 consumption where critical capillary pO2 has been reached
- 15-20mmHg - reached with exercise at about 60% maximall metabolic rate
- Inflection of Lactate production- logarithmic increase
CO2 increases faster than O2 is consumed - inflectionpoint
5
Q
RER measurements
A
Measured with slope of VCO2 vs Vo2
6
Q
CPET
A
- cardiopulmonary exercise testing
- exercise until exhaustion
- cardiac vs. respiratory threashold
- pre and post spirometry
- lactate and ABG
- O2 consumption CO2 production
- Tidal volume
- RR
- Minute ventilation
7
Q
CPET indications
A
- unexplained dyspnea
- undiagnosed exercise intolerance
- lung/heart transplant suitability
- pre-op evval
- dertermination of disability
- HF prognostication
8
Q
Exercise limitations
A
#1 - CARDIAC pulmonary muscular deconditioning obesity poor effort/motivaton
9
Q
Normal cardiac change during exercise
A
80-90% of predicted value is normal
10
Q
Lactate change for anaerobic metabolism
A
6-7
11
Q
Normal FEV1/FVC
A
70% is preserved
