19. Plaque induced gingival diseases, modified by systemic medication Flashcards

1
Q

Diabetes effect on Gingivitis

A
  • Level of diabetic control important in determining extend of periodontal disease
  • Decreased salivary flow
  • Predisposition to candidiasis, burning mouth, abcess formation
  • Impaired healing=>poor leukocyte function
  • Reduction in growth and proliferation of CT=>hyperglycemic environment
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2
Q

Leukemia effect on gingivitis

A
  • Abnormal proliferation of leukocytes in blood and marrow
  • Increased bleeding
  • Paleness of mucosa
  • Swollen, glazed, spongy tissues=>deep red to purple
  • Gingival enlargement=>interdental papilla folllowed by marginal and attached
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3
Q

Linear gingival erythema effect on gingivitis

A

*Can occur from Immunosuppression=>HIV
* 2-3 mm marginal band of intense erythema in free gingiva
* May extend to attached gingiva or alveolar mucosa
* May be localised but more commonly is generalised

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4
Q

Drugs that can cause gingival enlargement

A
  • Anticonvulsants(pheyntoin, sodium valproate)
  • Immunosuppressants(cyclosporin A)
  • Calcium channel blockers(Nifidepine, verapamil)

-Phenytoin causes gingival enlargment in 50% of users

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5
Q

The gingival enlargement mechanism is linked to

A
  • Excessive fibroblast production
  • Increased production of CT extracellular matrix
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5
Q

Characteristics of gingival enlargement due to systemic medications

A
  • Common in anterior gingiva
  • Higher prevelance in children
  • Onset within 3 months
  • Found in gingiva with or without bone loss
  • Pronounced repsonse in relation to amount of plaque present
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