17. Plaque induced gingival diseases, modulated by sex hormones

Question 1

Types of plaque induced gingival diseases modified by sex hormones

Answer 1

• Puberty associated gingivitis
• Menstrual cycle associated gingivitis
• Pregnancy associated gingivitis

Question 2

Pregnancy effect on periodontal disease

Answer 2

• Increaed plasma hormone levels(increased bleeding, gingival overgrowth, exudate and GCF)
• Estrogen affects salivary peroxidases
• Increased growth of seletive pathogens
• Estrogen increases inflammation
• Estrogen affects degree of keratinisation of CT ground substance
• Pregnancy granuloma can develop
• Gingivitis in response to low plaque levels

-salivary perioxidases active against mo
-Increased risk in 2nd and 3rd trimesters

Question 3

Puberty effect on periodontal disease

Answer 3

• Steroid hormones=>increased inflammatory mediators
• Gingivitis

Gingivitis in repsonse to relatively low levels of plaqque

Question 4

Menstrual cycle effect on periodontal disease

Answer 4

• Overt gingival changes rare w/ menstrual cycle
• Increased exudate/inflammatory exudate
• Not clinically observable