1.4 Innate Immunity Lec 1 Flashcards
Eosinophil stains ____ with Wright’s stain?
red
Eosinophils are in high or low levels in blood?
low
Eosinophil can or cannot interact with antibodies? phagocytic or not?
CAN interact with antibodies therefore they can be phagocytic
Eosinophil are important for?
worm and parasitic infections
elevated levels of eosinophils are associated with?
allergies or asthma
Eosinophil granules contain?
- Eosinophil cationic protein
- Major basic protein
- Eosinophil peroxidase
with Wright’s stain, Basophils are what color?
dark blue
Basophils are in high or low levels in blood?
low
Basophils contain ____-filled granules
histamine-filled granules
Basophils activation is important in? Promotes?
important in allergies
*Promotes inflammation
Mast cells are related to?
basophils
Mast cells stain?
dark blue in wright’s stain
where are Mast cells found?
in tissues
Mast cells contain ____-filled granules? important in??
histamine-filled granules
*important in allergy symptoms
Two types of mast cells?
1) connective tissue mast cell
2) mucosal mast cell
monocytes are part of what system?
part of reticuloendothelial system
are monocytes a macrophage?
yes!
each macrophage/monocyte has a _____ nucleus? EXCEPT?
bilobed
*Except for osteoclast each macrophage is phagocytic
Monocyte-macrophages present antigens to?
T-cells
Monocyte-macrophages can opsonize?
antibody-bound antigens
monocytes of blood develop into ______ at inflammation?
Inflammatory macrophage
monocytes of blood develop into ______ in liver?
Kupffercells
monocytes of blood develop into ______ in lungs?
alveolar macrophages
monocytes of blood develop into ______ in spleen?
splenic macrophages
monocytes of blood develop into ______ in brain?
microglial
monocytes of blood develop into ______ in bone?
osteoclasts
monocytes of blood develop into ______ macrophages?
peritoneal macrophages
