1- Pathologie - médiateurs Flashcards

1
Q

Principaux médiateurs de la vasodilatation (2)

A

Histamine
Prostaglandines (PS)

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2
Q

Principaux médiateurs de la perméabilité vasculaire (3)

A

Histamine
Complément
Leucotriènes (LT)

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3
Q

Principaux médiateurs de la chimiotaxie (3)

A

Chimiokines
Leucotriènes (LT)
Complément

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4
Q

Principaux médiateurs de la fièvre (2)

A

Protaglandines (PS)
Citokines

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5
Q

Principaux médiateurs de la douleur (3)

A

Bradykinines
Neuropeptides
Prostaglandines (PS)

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6
Q

Principaux médiateurs du dommage tissulaire (2)

A

Enzymes lysosomiales
Radicaux libres (ROS)

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7
Q

Provenances de l’histamine (3)

A

Mastocytes
Basophiles
Thrombocytes (plaquettes)

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8
Q

Provenance des protéines du complément

A

Foie

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9
Q

Provenance des kinines

A

Foie

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10
Q

Provenances des prostaglandines (PS) (2)

A

Mastocytes
Leucocytes

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11
Q

Provenances des leucotriènes (LT) (2)

A

Mastocytes
Leucocytes

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12
Q

Provenances du facteur d’activation plaquettaire (PAF) (2)

A

Mastocytes
Leucocytes

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13
Q

Provenances des cytokines (3)

A

Immunologie et pathologie V : macrophages, cellules dendritiques, lymphocytes
Pathologie V (tableau) : macrophages, mastocytes, cellules endothéliales

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14
Q

Provenance des chimiokines

A

Leucocytes (surtout macrophages activés)

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15
Q

Provenances de l’oxyde nitrique (NO) (2)

A

Macrophages
Cellules endothéliales

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16
Q

Provenances des enzymes lysosomiales (2)

A

Neutrophiles
Macrophages

17
Q

Provenances des radicaux libres (ROS) (2)

A

Macrophages
Neutrophiles

18
Q

Provenances des neuropeptides (2)

A

Nerfs sensitifs
Leucocytes

19
Q

Actions histamine (2)

A

Vasodilatation
Perméabilité vasculaire

20
Q

Actions complément (4)

A

Activation leucocytes
Chimiotactisme
Complexe attaque membranaire (MAC)
Perméabilité vasculaire

21
Q

Actions kinines (4)

A

Perméabilité vasculaire
Vasodilatation
Contraction musculaire lisse
Douleur

22
Q

Actions prostaglandines (3)

A

Douleur
Fièvre
Vasodilatation

23
Q

Actions leucotriènes (LT) (2)

A

Chimiotactisme
Perméabilité vasculaire

24
Q

Action facteur activation plaquettaire

A

Chimiotactisme
Activation plaquettes

25
Q

Actions cytokines (3)

A

Activation endothéliale
Fièvre
Hypotension

26
Q

Action chimiokines

A

Chimiotactisme

27
Q

Actions oxyde nitrique (NO) (2)

A

Diminuer réponse inflammatoire
Effet bactéricide

28
Q

Action radicaux libres (ROS)

A

Destruction tissu lésé et agent inflammatoire

29
Q

Action enzymes lysosomiales

A

Destruction tissu lésé et agent inflammatoire