(XIII)Spiral bacteria Spirochaete (1)Borrelia spp.

Question 1

Where is Borrelia burgdorferi endemic?

Answer 1

NE US

Question 2

B. recurrentis (relapsing fever) is transmitted by […]

B. burgdorferi (lyme disease) is transmitted by […]

Answer 2

B. recurrentis (relapsing fever) is transmitted by louse

B. burgdorferi (lyme disease) is transmitted by hard ticks

Question 3

Borrelia spp. infection

Clinical Presentation
1. B. recurrentis, B. duttoni
[…]

2. B. burgdorferi
   […]

Answer 3

Borrelia spp. infection

Clinical Presentation
1. B. recurrentis, B. duttoni
- Relapsing Fever due to antigenic variation

2. B. burgdorferi
   - Lyme disease
   - Stage 1: Erythema Chronicum migrans (ECM) + systemic including CNS
   - Stage 2: CNS, heart, musculoskeletal
   - Stage 3: chronic skin, joint, CNS disease

Lyme disease:
- congenital infection may occur

Question 4

Diagnosis for B. recurrentis (relapsing fever) is […]

Diagnosis for B. burgdorferi (lyme disease) is […]

Treatment for both is […]

Answer 4

Diagnosis for B. recurrentis (relapsing fever) is stained blood film

Diagnosis for B. burgdorferi (lyme disease) is serology (culture difficult)

Treatment for both is doxycycline