(XII) Obligate Intracellular Pathogens (1)Coxiella burnetti

Question 1

Characterize (3) : Coxiella

Answer 1

(1) Gram (-) rod
(2) Obligate intracellular
(3) Spores

Question 2

Coxiella Burnetii infection

Transmission: zoonosis (milk, excreta, birth products) (transmission to man usually via aerosolised resistant endospores which are virulent in months)

Clinical presentations:
[…]

Answer 2

Coxiella Burnetii infection

Transmission: zoonosis (milk, excreta, birth products) (transmission to man usually via aerosolised resistant endospores which are virulent in months)

Clinical presentations:
Q Fever
- Acute Q fever: mild pneumonia (similar to M. pneumoniae), PUO, flu-like illness, rash is rare
- Chronic Q fever: endocarditis (native valve or prosthetic)

Question 3

Diagnosis of C. burnetii infection is usually with

[…]

Answer 3

Diagnosis of C. burnetii infection is usually with

Serology

Question 4

Treatment of acute Q fever is with

[…]

Answer 4

Treatment of acute Q fever is with

Doxycycline + Rifampicin