Why Do Infants Wheeze Flashcards

1
Q

Wheeze

A

Breathing that makes a high pitched whistling or squeaking sound from the chest

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2
Q

Do wheezes occur more commonly on inspiration or expiration

A

Expiration

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3
Q

What can be heard when auscultation a Croup patient

A

inspiratory stridor

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4
Q

What can be heard when auscultation a Bronchiolitis patient

A

Inspiratory crackles

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5
Q

What creates a wheeze

A

Air flowing rapidly though an obstructed airway

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6
Q

Characteristics of preschool wheeze

A

Episodes triggered by viral colds
Few symptoms between attacks

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7
Q

Outcomes of preschool wheeze

A

Grow out of it - 75%
Develop into asthma - 25%

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8
Q

What increases risk of preschool wheeze

A

Smoking in pregnancy
Air pollution

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9
Q

How does smoking during pregnancy affect the child’s airway structure

A

Increased distance between alveolar attachments

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10
Q

What can accumulate in the lungs as a result of air pollution

A

Particulate matter

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11
Q

Which immune cells can contain carbon as a result of air pollution

A

Macrophages

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12
Q

Presentations of preschool wheeze

A

Cough without cold
Nighttime cough
Wheeze
Occurs in attacks triggered by colds, few symptoms between attacks

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13
Q

How can air pollution effect the placenta

A

Inhaled particles enter circulation and accumulate in placental phagocytic cells

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14
Q

Factors increasing risk of preschool wheeze becoming asthma

A

Severe wheeze events
Prematurity
Mater al asthma
First reported wheeze in September
Frequent wheeze events
Atopy
Bronchiolitis

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15
Q

Why should children under 6 use a spacer for inhalers

A

Can’t coordinate breathing and puffing

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16
Q

Triggers of asthma

A

Exercise
Pollen
Viral colds
Temperature
Laughing
Acid reflux
Perfume

17
Q

Cellular abnormalities in asthma

A

Goblet cell hyperplasia
Thick sub basement membrane
Cellular infiltrate
eosinophils and T cells

18
Q

Bacterial lysates

A

medicines made from bacterial cells that are broken down and are intended to stimulate the immune system to recognise and fight infections

19
Q

MV130

A

Bacterial lysate tongue spray for asthma

20
Q

Are bacterial lysates currently used for asthmatics

A

Not yet - future treatment

21
Q

The farm effect

A

Decreased wheeze and asthma risk in farm kids