Problems Of The Male Reproductive System Flashcards
What joins the urethra within the prostate
Ejaculatory duct
What are the 4 main areas of the prostate
Peripheral
Central
Transition
Anterior fibromuscular stroma
What hormone causes growth of the prostate
Testosterone
Is the fluid secreted by the prostate and added to seminal fluid acid or alkali
Alkali
Largest zone of the prostate
Peripheral
What types of tissue make up the prostate
Glandular
Fibromuscular
What zone of the prostate does cancer tend to start in
Peripheral
Why does benign prostatic hyperplasia occur more with advancing age
Longer exposure to testosterone
What causes BPH
Age related enlargement
Testicular androgens
Oestrogens
Prostatic stromatolites and epithelial tissue interactions
Nuerotransmitters
What molecule’s action is blocked in the epithelium preventing apoptosis leading to BPH
Estradiol
What is testosterone converted to in stromal cells and epithelial cells
Stromal - estradiol
Epithelial - DHT
What does activation of the estrogen receptor beta receptor in epithelial cells and estrogen receptor alpha in stromal cells lead to
Beta Apoptosis
Alpha proliferation
What causes BPE symptoms
Narrowing of urethra
BPE symptoms
Weak/interrupted urine flow
Nocturia
Frequent urination
Trouble urinating
Pain/burning on urination
Blood in urine or semen
2 acronyms for BPE symptoms
SHITE - Slow stream, Hesitancy, Intermittent flow, Terminal dribbling, Emptying incomplete
FUN - Frequency, Urgency, Nocturia
What age does BPE usually occur
40+