Age Related Changes 1 Flashcards
What causes ageing at the cellular level
Accumulation of molecular and cellular damage
Risks associated with ageing
Age related changes
Co morbidities
Poly pharmacy
Why do drugs stay in the system longer with increasing age
Not metabolised as effectively, esp drugs metabolised by P450
What causes accumulation of damage throughout life
Genetics
Pre conception influences
Accidents
Toxin exposure
Decr regenerative capacity
Factors effecting ageing
Smoking, nutrition, asthma
Hereditary conditions
Gender, development,
Air pollution, smoking, occupational exposures
Infections
Socioeconomic status
Co morbidities
Ways to decr effects of ageing
Healthy diet
Decr alcohol
Stop smoking
Regular exercise
Stay mentally active
Social interactions
How does smoking cessation effect ageing
Returns reduction in function to normal rate - doesn’t return lungs to pre smoking state
Dementia risk factors
Physical inactivity
Midlife obesity
Low educational attainment
Midlife hypertension
Depression
Smoking
Diabetes