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PRNU 228 > Week 9 Reproductive System > Flashcards

Week 9 Reproductive System Flashcards

1
Q

ethinyl estradiol & drospirenone (Yasmin) class

A

Oral Contraceptives – Combination estrogen/progesterone

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2
Q

ethinyl estradiol & drospirenone (Yasmin) EPA

A

Suppresses secretion of FSH & LH, thus preventing ovulation.
Progesterone thickens cervical mucus; Prevents endometrium thickening.
Drospirenone works similarly to spironolactone thereby decreasing ankle edema & treating PMS symptoms

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3
Q

ethinyl estradiol & drospirenone (Yasmin) therapeutic use

A

prevent pregnancy
relieve PMS symptoms
stabilize menses
prevent uterine/ovarian cancer, PID, ovarian cysts

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4
Q

ethinyl estradiol & drospirenone (Yasmin) ADRs

A

thromboembolism
abnormal uterine bleeding
promote growth of existing breast cancer
potential risk for HTN
hyperkalemia (drospirenone)

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5
Q

ethinyl estradiol & drospirenone (Yasmin)
contraindications

A

teratogenic
BRCA1 gene mutation
ACE inhibitors
effectiveness decreased by anti seizure and antifungal

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6
Q

ethinyl estradiol & drospirenone (Yasmin) interventions and education

A

Confirm absence of pregnancy FIRST
Additional method of birth control during 1st cycle of pills
Avoid salt substitutes (drospirenone)
Monitor K+ due to potential for hyperkalemia (drospirenone)
Monitor BP
Monitor for s/sx of DVT/PE/MI/Stroke
Avoid smoking
Monitor pattern & amt of uterine bleeding
D/C if any indication of breast cancer

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7
Q

levonorgestrel (Mirena) class

A

contraceptive IUD

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8
Q

levonorgestrel ( Mirena) therapeutic use

A

pregnancy prevention
treat PMS symptoms and heavy periods
emergency contraceptive
endometriosis and fibroids

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9
Q

levonorgestrel ( Mirena) ADRs

A

acne, migraines, vaginitis, ovarian cysts, hair loss or unwanted hair growth, decreased libido, PID, ectopic pregnancy, uterine perforation

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10
Q

levonorgestrel ( Mirena) contraidications

A

teratogenic
PID
past or current cancer of breasts, cervix, uterus
less than 6 weeks postpartum

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11
Q

levonorgestrel ( Mirena) interventions and education

A

Confirm absence of pregnancy FIRST
Avoid smoking
Monitor pattern & amt of uterine bleeding
Teach client to feel for IUD strings with a clean finger once/month after menses
Call provider if strings seem shorter or longer than usual/can’t locate string/unable to feel IUD
Report any sudden abdominal pain/cramping/vaginal bleeding, abnormal discharge, fever

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12
Q

conjugated estrogen & medroxyprogesterone acetate (Prempo) class

A

Estrogen and Progesterone HRT

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13
Q

conjugated estrogen & medroxyprogesterone acetate (Prempo) EPA

A

Binds to estrogen receptors and substitutes the fluctuating amounts of estrogen into a more stable amount of estrogen to prevent symptoms.
Adding in progesterone suppresses tissue growth in the uterus thereby preventing hyperplasia of uterine lining.

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14
Q

conjugated estrogen & medroxyprogesterone acetate (Prempo) Therapeutic Use

A

relieves symptoms of menopause

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15
Q

conjugated estrogen & medroxyprogesterone acetate (Prempo) ADRs

A

nausea
HTN
vaginal bleeding
edema
weight gain
breast cancer
thromboembolic disorders

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16
Q

conjugated estrogen & medroxyprogesterone acetate (Prempo) contraindications/interactions

A

history of thromboembolic events
suspected or confirmed reproductive cancer

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17
Q

conjugated estrogen & medroxyprogesterone acetate (Prempo) interventions and education

A

monitor BP
monitor DVT, PE, MI, stroke symptoms
do not smoke
stop 4 weeks prior to surgery
apply intravaginal or transdermal
monitor uterine bleeding and report persistent vaginal bleeding
discontinue at any indication of cancer

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18
Q

conjugated equine estrogen (Premarin) class

A

estrogen HRT

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19
Q

conjugated equine estrogen (Premarin) EPA

A

Binds to estrogen receptors and substitutes the fluctuating amounts of estrogen into a more stable amount of estrogen to prevent symptoms

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20
Q

conjugated equine estrogen (Premarin) therapeutic use

A

relieves symptoms of menopause

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21
Q

conjugated equine estrogen (Premarin) ADRs

A

nausea
HTN
endometrial hyperplasia
thromboembolic disorders

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22
Q

conjugated equine estrogen (Premarin) contraindications and interactions

A

history of thromboembolic events
suspected or confirmed reproductive cancer

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23
Q

conjugated equine estrogen (Premarin) interventions and education

A

monitor BP
monitor signs of DVT, PE, MI, stroke
avoid smoking
stop 4 weeks prior to surgery
apply intravaginal or transdermal at bedtime
monitor uterine bleeding, report persistent vaginal bleeding
discontinue if signs of cancer

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24
Q

testosterone (Androderm) class

A

androgen - testosterone

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25
testosterone (Androderm) therapeutic use
treatment of male hypogonadism, delayed puberty, and testicular failure treatment of breast cancer in females Hormone therapy for transgender males
26
testosterone (Androderm) EPA
synthetic testosterone
27
testosterone (Androderm) administration
PO, IM, intranasal, transdermal, buccal upper gums, subQ
28
testosterone (Androderm) ADRs
development of male characteristics hypertension growth of prostate cancer gynecomastia hepatotoxic premature bone growth plate closure in children increased irritability and aggression
29
testosterone (Androderm) interventions and education
educate about virilization effects screen for prostate cancer monitor growth of children and adolescents monitor liver function, weight, sodium educate about gynecomastia and mood changes
30
testosterone (Androderm) contraindications
teratogenic prostate cancer or BPH hypertension increase action of insulin/antidiabetic meds increases risks of warfarin
31
finasteride (Proscar) class
5-Alpha Reductase Inhibitor
32
finasteride (Proscar) therapeutic use
BPH and male pattern baldness reduces risk of prostate cancer
33
finasteride (Proscar) EPA
Inhibits 5-alpha reductase, the enzyme responsible for converting testosterone to 5-alpha DHT. inhibits metabolism of testosterone, causing decreased proliferation of prostatic cells reduces the enlargement of the prostate gland and mechanical obstruction of the urethra.
34
finasteride (Proscar) ADRs
reduced libido, ejaculate volume gynecomastia
35
finasteride (Proscar) interventions and education
pregnant nurse, caregiver, or pharmacist should not handle drug, especially if crushed baseline PSA cancer screening
36
finasteride (Proscar) contraindications and interactions
women, children, pregnancy caution with obstructive urinary disorders and live impairment
37
tamsulosin (Flomax) class
Alpha1-adrenergic blockers
38
tamsulosin (Flomax) therapeutic use
Treats BPH and improves urination
39
tamsulosin (Flomax) EPA
blocks alpha1-adrenergic receptors smooth muscle relaxation in the prostate and outlet of bladder increased urinary flow
40
tamsulosin (Flomax) ADRs
ejaculation irregularities, HA, dizziness
41
tamsulosin (Flomax) interventions and education
educate about altered ejaculation educate about orthostatic hypotension monitor BP change position slowly do not drive if dizzy
42
tamsulosin (Flomax) contraindications and interactions
do not take with ED drugs not for females and children caution with hypotension
43
Sildenafil (Viagra) class
Phosphodiesterase Type 5 (PDE5) Inhibitors
44
Sildenafil (Viagra) therapeutic use
erectile dysfunction
45
Sildenafil (Viagra) EPA
blocks PDE5 – which normally ends an erection
46
Sildenafil (Viagra) ADRs
priapism HA hypotension fainting dizziness rare: hearing or vision loss
47
Sildenafil (Viagra) interventions and education
go to ER for erection over 4 hours take 1 hour prior to sex high fat foods decrease effects do not take within 24 hours of nitroglycerin for angina
48
Sildenafil (Viagra) contraindications and interactions
caution with recent cardiac events grapefruit juice increases effects with tamsulosin = hypotension
49
oxybutynin (Ditropan) class
Anticholinergic/Urinary Antispasmodics
50
oxybutynin (Ditropan) therapeutic use
spastic bladder conditions (neurogenic bladders), overactive bladders: incontinence, urgency, frequency
51
oxybutynin (Ditropan) EPA
blocks muscarinic receptors in the detrusor muscle = bladder relaxation + contraction of internal sphincter
52
oxybutynin (Ditropan) ADRs
antichoolinergic = dry dry mouth, constipation, blurred vision, dilated pupils, dry eyes decreased sweating = increased temp
53
oxybutynin (Ditropan) interventions and education
monitor for anticholinergic effects or crisis urinary retention can cause UTI and bladder distention caution for hyperthermia drink lots of water increase fiber intake
54
oxybutynin (Ditropan) contraindications and interactions
closed angle glaucoma myasthenia gravis GI obstruction grapefruit juice and antifungals increase toxicity
55
bethanechol (Urecholine) class
Cholinergic/Urinary Stimulant
56
bethanechol (Urecholine) therapeutic use
no-obstructive urinary retention
57
bethanechol (Urecholine) EPA
activates muscarinic receptors in the detrusor muscle that lines the bladder = bladder contraction. Also relaxes internal sphincter.
58
bethanechol (Urecholine) ADRs
cholinergic = wet salivation, lacrimation, diarrhea Bronchoconstriction hypotension and bradycardia
59
bethanechol (Urecholine) interventions and education
monitor BP, HR, respiratory monitor urinary output educate on hypotension
60
bethanechol (Urecholine) contraindications and interactions
hyperthyroidism, asthma, GI ulcers, obstructive urinary retention

PRNU 228 (19 decks)

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