Infection meds Flashcards
amoxicillin (Amoxil) class
penicillin
amoxicillin (Amoxil) therapeutic use
broad spectrum for gram negative bacteria, treatment of infection or prophylaxis
some gram positive for skin, soft tissue, respiratory, GI or GU infection
amoxicillin (Amoxil) EPA
inhibits bacterial cell wall synthesis, interruption of cell wall synthesis causes cell death
amoxicillin (Amoxil) ADRs
hypersensitivity
anaphylaxis
GI effects
renal and hepatic impairment
thrombophlebitis w IV administration
amoxicillin (Amoxil) contraindications and interactions
allergy to penicillin or cephalosporin
caution with severe renal impairment
safe in pregnancy and lactation
amoxicillin (Amoxil) interventions and education
monitor GI symptoms
monitor for candidiasis infection
epinephrine given for anaphylaxis
monitor BUN and creatinine
cefazolin (Ancef) class
cephalosporins
cefazolin (Ancef) therapeutic use
surgical prophylaxis
cefazolin (Ancef) EPA
inhibits bacterial wall synthesis
cefazolin (Ancef) interventions and education
monitor GI symptoms
monitor for candidiasis infection
epinephrine given for anaphylaxis
monitor BUN and creatinine
cefazolin (Ancef) contraindications and interactions
safe in pregnancy and lactation
causes bad side effects when taken with alcohol
N/V, flushing, dizziness, headache
aztreonam (Azactam) class
monobactams
aztreonam (Azactam) therapeutic use
only work on gram neg
urinary infections
lower respiratory infections
some abdominal and gyn infections
aztreonam (Azactam) EPA
inhibits bacterial wall synthesis
aztreonam (Azactam) ADRs
pain, phlebitis, and inflammation of IV
superinfection
seizures
GI effects and hypersensitivity
aztreonam (Azactam) contraindications and interactions
caution with ceph or pen allergy
not sure of safety in pregnancy and lactation
aztreonam (Azactam) interventions and education
monitor BUN and creatinine
monitor bowel function
IV form incompatible with many drugs
furosemide can increase blood levels
gentamicin class
aminoglycosides
gentamicin therapeutic use
narrow spectrum for gram neg
gentamicin EPA
disrupts protein synthesis to alter function and replication of bacteria
gentamicin ADRs
nephrotoxicity: polyuria, dilute urine, proteinuria, elevated BUN and creatinine
ototoxicity: tinnitus, headache, ataxia, vertigo
GI effects
gentamicin contraindications and interactions
avoid in pregnancy - risk for congenital deafness
avoid vanco, ceph, pen, or neuromuscular blockers
avoid in patients w tinnitus, vertigo, hearing loss
gentamicin interventions and education
monitor BUN and Creatinine
monitor serum levels
monitor for nephrotoxicity and ototoxicity
make sure patient is hydrated before starting therapy
ciprofloxacin (Cipro) class
fluoroquinolones