Week 8 pt 2

Question 1

10x risk of African and Caribbean migrants for what condition?

Answer 1

schizophrenia

Question 2

schizophrenia is associated with mutations in __ out of __ chromosomes

Answer 2

21 out of 23

Question 3

risk factors for schizophrenia (5)

Answer 3

• man
• older father
• atypical prenatal development
• poor social adjustment
• deficient psychomotor functioning

Question 4

Minor Physical Anomalies with schizophrenia (3)

Answer 4

• High-steepled palate
• Partial webbing of two middle toes
• Especially wide or narrow-set eyes

Question 5

__% reduction in life expectancy in schizophrenia

Answer 5

20%
(40% of deaths attributable to suicide)

Question 6

Symptoms of Anti-Cholinergic (4)

Answer 6

• dry mouth
• urinary retention
• blurred vision
• constipation

Question 7

4 types of Extrapyramidal (too much antipsychotic)

Answer 7

• Tardive Dyskinesia – symptoms irreversible but Vitamin E can prevent further deterioration
• Akathisia – subjective unpleasant feeling of restlessness
• Pseudo-Parkinsonism
• Acute Dystonia

Question 8

Medication being studied for people who are treatment resistant with at least 2 antipsychotic meds for schizophrenia

Answer 8

Clozapine

Question 9

Families of persons with affective disorders are ____ more likely to develop MDD or Bipolar/mood disorder

Answer 9

10 times

Question 10

trait or genetic predisposition underlying one’s baseline range and lifelong ability to feel pleasure

Answer 10

Hedonic Tone/ Responsiveness

Question 11

Hedonic Tone/ Responsiveness is caused by

Answer 11

Dysfunction of mesolimbic and mesocortical pathways

Question 12

LOW Hedonic Tone causes an increased risk for: (3)

Answer 12

anhedonia, depression, and dysthymia

Question 13

What explains 3-6 week lag in tx response time

Answer 13

Hippocampal neurogenesis

Question 14

Internalization of sxs and negative emotionality in MALES in childhood is found to be associate with maternal emotional distress in what trimester

Answer 14

first

Question 15

Increase risk of autism, Tourette’s, OCD, and ADHD is found to be associate with maternal emotional distress in what trimester

Answer 15

first

Question 16

Internalizing sxs in FEMALE adolescence is found to be associate with maternal emotional distress in what trimester?

Answer 16

third

Question 17

associated with more fearful and reactive bx in female infants as compared to male infants

Answer 17

Elevated milk cortisol levels during lactation

Question 18

associated with increased risk of mood disorder in children

Answer 18

Older maternal age

Question 19

diagnosis with Reduced connections between amygdala and PFC

Answer 19

GAD

Question 20

Disproportionate activation of amygdala when viewing negative expressions and neutral ones

Answer 20

social anxiety

Question 21

Increase activation of amygdala & periaqueductal grey during what?

Answer 21

panic attack

Question 22

Activation in which lobe: “Anxious Apprehension” vs. “Anxious Arousal”

Answer 22

• Anxious App = increased activation in left frontal lobe (i.e., Broca’s)
• Anxious Arousal = increased activation in right temporal lobe (i.e., increased sensitivity to environmental sounds and noises.)