Week 2 - Study Guide Flashcards
Nerves
Bundles of fibers (a bunch of axons)
OUTSIDE THE CNS
Tracts
- Bundles of fibers (a bunch of axons)
IN THE CNS - Ascending - sensory in to CNS
- Descending - CNS to motor output
Ganglia
- Nerve cell bodies in PNS
- Around the spinal cord
Nuclei
- Nerve cell bodies in CNS
- in core of brain
- Processing information
- Surrounded by white matter
White Matter
- Axons
- Cable connecting all processors of white
- Myelinated axons or dendrites
- Deeper in brain
- Cable connecting parts
- Also called Tracts
Corpus Callosum
- Connects R & L hemispheres
- Projection pathways allowing the cortex to send motor outputs towards the spinal cord to PNS
Gray Matter
- cell bodies
- Powerhouse Processors
- non-myelinated
- edge of cortex
- processing
- integration
CNS Regions of the Brain
- Cerebrum - outer
- Diencephalon - core
- Brain Stem - brain/spinal cord
- Cerebellum - tiny brain
Ventricles - connect the 4 brain regions
1 & 2 - Lateral Ventricles - cerebral hemispheres (looks like horns of ram)
- in the diencephalon - in between the two sides of the thalamus
- hindbrain - in between the pons and the cerebellum
What disease is associated with the ventricles
Cerebral Palsy
Shunt to drain fluid into the abdominal cavity
What are the ventricles lined with?
Ependymal cells
which have cilia
What are the ventricles filled with
CSF
What are meninges?
Tough, useful membranes that have multiple layers that surround the brain
Protection for the brain
Bone, CSF, BBB
What do the membranes do?
- Cover the CNS
- Adhere blood vessels to the brain
- Contains CSF
- Form partitions in the skull
What are the three types of meninges?
- Dura Mater
- Arachnoid Mater
- Pia Mater
Dura Mater
- Outer layer
- Strong Fibrous CT
- Holds brain and spinal cord to bone
- Sack encloses the brain and spinal cord provising some protection
Arachnoid Mater
- Spider Web
- Middle Layer
- Light fibrous material off of dura mater
- Connects to Pia Mater
What is the subarachnoid space?
Space In between the arachnoid mater where the location of the CSF will travel
What is CSF composes of?
- Watery solution - intra & extracellular
- Modified from plasma - less electrolyte and protein
- Constant volume is the goal
Functions of the CSF
- Buoyancy to CNS
- Protects CNS from trauma
- Nourishment & Chemical signals
What is CSF produced by?
Choroid plexus - blood vessel
CSF circulation -
- Choroid Plexus makes CSF
- CSF flow into the ventricles
- from lateral ventricles
- down to 3rd ventricle
- to cerebral aqueduct
- to 4th ventricle
- to the subarachnoid space
- back toward teh top of the head
- CSF is absorbed into the dural venous sinuses via the arachnoid villi
Arachnoid Villi
Location where the CSF leaves the CNS region back into a vein called the Dural Venous Sinus
Dural Venous Sinus
Vein where the CSF leaves the CNS and enters the Dural Venous Sinus
External Hydrocephalus
- External Blockage
- Build up of fluid in subarachnoid space pushing inward on the brain
- Compresses brain
Internal Hydrocephalus
- Internal Blockage
- Fluid would start to back up causing internal pressure
Compression inside out - Ventricles out
- Expands
CSF Issues
Spina bifida
Cerberal Palsy - shunt drain into abdomen
The Brains Convolutions
folds of the surface of the brain
Cortex Convolutions
Surface of the brain
Gyri
Bumps
Sulci
Shallow groove
Opposite of bump
Fissure
Deeper Groove
Deep Dividing Line
Central Sulcus
- Divides Frontal Lobe from Parietal Lobe
- where you go from motor activity in frontal cortex to the sensory processing of the parietal lobe
Lateral Sulcus
Dividing line between the temporal lobe and frontal lobe
Cerebral longitudinal fissure
- Divides the L and R cerebral hemispheres
- Place that connects the sides of the hemispheresTr
Transverse Fissures
- Divides cerebellum (baby brain) from Occipital Lobe and Temporal Lobe above it
- Divides Cerebellum below from cerebrum above
- Things above the fissure are cerebrum
- Things below cerebellum and brain stem
Cerebrum
Referring to the cortex of all the lobes and the diencephalon (omitting the cerebellum and brain stem)
4 Brain Regions
- Cerebrum
- Diencephalon
- Brain Stem
- Cerebellum
Parts of the Cerebrum
L & R cerebral hemisphere
Diencephalon
Parts of the Diencephalon
- Epithalamus
- Thalamus
- Hypothalamus
Parts of the Brain stem
(Region below the Diencephalon)
- Midbrain
- Pons
- Medulla Oblongata
Parts of the Cerebellum
Baby brain under the cerebrum
Name the four lobes
- Frontal Lobe
- Parietal Lobe
- Temporal Lobe
- Occipital Lobe
Frontal Lobe - Functions
MOTOR
1. Movement - Voluntary
2. Memory
3. Reasoning - Critical thinking
4. Emotion & Verbal communications
5. Distinguishes humans from everything else
Parietal Lobe - Functions
SENSORY
1. Body Mapping
2. Sensory localization
Temporal Lobe - Functions
EARS
1. Hearing
2. equilibrium
3. Memories of sensory experiences
Occipital Lobe - Functions
EYES
1. Vision
2. Visual interpretation
3. Integrating eye movement
Which lobe does motor?
Frontal Lobe
Which lobe does sensory?
Pariteal Lobe
Four Areas in the Frontal Lobe that do motor
- Primary Motor Cortex M1 - COMMAND
- PreMotor - Planning
- Broca’s area
- Frontal Eye Fields
Primary Motor Cortex -M1
MOTOR COMMAND CENTER
1. Voluntary movement
2. Pyramidal cells (corticospinal tracts - white matteer CNS)
Brain to spinal
Descending pathways
3. Somatotopic - body mapping
4. Gyrus in front of central sulcus
Premotor
PLANNING
1. Learned motor skills
2. Repetitious activity or patterns and planning
3. Premotor turns on before Primary Motor Cortex
Broca’s Area
IN the frontal lobe
1. Motor aspects of speech
Frontal Eye Fields
Frontal Lobe
1. Voluntary eye movements
Sensory Areas of the cortex in parietal lobe
- Primary somatosensory cortex
- Somatosensory association area (cortex)
- Visual Areas - Primary & Association
- Auditory Areas - primary & Association areas
Visual Neglect
- Nothing wrong with eyes
- Structures of vision are fine
- But visual field is affected
- Can only draw half of what you see
- Association - structure - sensory to put all together
- Phineas Gage - Prefrontal cortex damage
Primary Somatosensory Cortex
- Localization
- Localize muscles 7 skin stimuli
- Sensory Homunculus - visual - lots of face, tongue, hands, fingers
Somatosensory association area (cortex)
- Sensory integration & analysis
- What to do, need to integrate, analyze
- Association Neuron - Presynaptic sensory afferent –> interneuron association –> Efferent motor
Visual Areas - Primary & Association
- Occipital Lobe
- Experience - life taught - p/u pen
- Basic memory part - orient body to p/u pen - higher thinking - frontal lobe -
- Parietal & Frontal Lobe
- Primary - Big Picture Visual
- Association area - info stitch together - more holistic view of how/what it is and oriented to us and our environment
Auditory Areas - Primary & Association
- Temporal Lobe
- Will allow for interpretation and integration of auditory information
Lateralization
Division of labor between hemispheres
Cerebral Dominance
- Left Hemisphere - Math, Logic, Language (Analytical - Sequence) in 90% of people
- Right Hemisphere - Insight - visual-spatial skills, intuition, artistic skills, holistic, unitary, creative
Meant by Association Areas?
- Think of an area that will help put the pieces together
- Takes individual pieces of information and stitches them together.
- So we have appropriate interpretation - INTEGRATION
- Analysis of info that is available to us
Commissures
The way you connect L & R hemispheres through the corpus callosum
Association fibers
- Only connect regions w/in the same hemisphere
- Connected processed information from one area w/in the same hemisphere
Projection fibers (corona radiata)
- Theses will be motor pathways
- Descending Pathways
- cortico spinal tracts
- Connecting the cerebrum
- descending down to the medulla oblongata
- where you have the crossing over at the decussation of pyramids
- allowing the R side to control the L and vice versa
Cerebrum - What they do
Motor
Sensory
Association
Brain Stem - what they do
- Basic Life Functions
- Respirations
- Homeostasis
Midbrain - what they do
Pupil Dilation
Startle Reflex
Pons - what they do
Bridge
Connects spinal cord, cerebellum, cerebrum
Medulla Oblongata - what they do
Site of decussation (crossover), vasomotor, breathing rate
Cerebellum - what they do
Online feedback & Coordination
Dysfunction - cerebral damage
- Dysmetria
- Cerebelar ataxia
- Intention Tremor
- Dysarthria
Dysmetria
Motor output is NOT in control
Imbalance of excitation * inhibition
Cerebelar ataxia
Cerebellum is not gone
Does not quite work right
Intention Tremor
- smooth in the middle motion
- as they get closer and closer to target - they correct, overcorrect, overcorrect as they hit the target
Dysarthria
In coordination of execution of speech
can understand speech but have a difficult time coordinating excitation & inhibition w/in the muscles of the oral cavity that are required for speech
Functions - Pons
Connects spinal cord, cerebellum, cerebrum
Functions - Epithalamus
Pineal gland - endocrine function
Functions - Midbrain
Pupil dilation
startle reflex
Functions - Thalamus
Routes information, cortical arousal
Functions - Basal Nuclei (ganglia)
Balances excitation and inhibition
Functions - Hypothalamus
Heart Rate
BP
Thermoregulation
Functions - Medulla Oblongata
Site of decussation (crossover), vasomotor, breathing rate
Limbic System
- Emotional Brain - frontal cortex &/or limits emotional expression
- Depressants (alcohol) deregulate emotional action
Reticular Formation
- ~ 100 brain stem nuclei
Has Four Functions
1. Arousal
2. Somatic Motor Control
3. ANS control
4. Pain Modulation
RF - Arousal
- Cortical arousal pathway created in the thalamus
- Think of it like a relay station - getting the info from the periphery - senses - (receptors) - to the RF - up t the thalamus
- RF –> Thalamus –> cortical activity
RF - Somatic Motor Control
- Help to regulate the descending motor pathways
- Helping to smooth out the motor output and help establish even more coordination
- Increases smoothness and coordination
RF -ANS Control
Respiratory & Cardio Centers
RF - Pain Modulation
Descending fiber can block pain transmission
Spinal Cord organization
Foramen Magnum –> conus medullaris at L1 vertebrae
Meaning that the cross-sectional pattern of the spinal cord actually stops
What you see beyond this area is spinal nerves
All of the CNS is housed in–
the meninges
dura, arachnoid, pia mater
The meninges extend all the way down to the structure called …
Filum Terminale
Filum Terminale
Helps to hold all of these meninges, or membranes, to the coccyx, ensuring that the integrity of this protection is maintained
What is the job of the spinal cord?
- It is all about bringing information:
In from the CNS out to PNS
-OR-
In from the PNS out to CNS
- Contains spinal reflex centers
Naming Pathways
Origins & Insertions
1. Where cell bodies (signal) originates
2. Where axons terminate
Sensory - ascending
or
Motor - descending