Vitamins and minerals Flashcards
water sol vitamin ex
B-complex group and vit C
water sol vitamins
dissolve in water
easily excreted in the urine
cant be stored in the body over long periods
daily intake required to prevent deficiencies
act as coenzymes or oxidation reduction agents
fat sol vitamins
in plant and animal foods
stored in the liver
slow metabolism
excreted via feces
toxic in excess
daily intake not required unless deficient
fat sol vitamins ex
A D E K
vitamin A
aka retinol, retinyl palmitate, retinyl acetate
fat soluble
food surces: liver, fish, dairy, egg yolks, dark leafy greens, yellow-orange veg
comes from carotenes
vitamin A functions
growth and development of bone and teeth
night and normal
vit a indications
-dietary supplement for infants, pregnant, nursing women
- deficiency (hyperkeratosis, night blindness)
- skin conditions (acne, psoriasis, keratosis follicularis
isotretinoin and vit a
result in additive effects and possible toxicity
vit a toxicity
- irritability, drowsiness, vertigo, delirium, coma, vomiting, diarrhea
- increased intracranial pressure in infants
- peeling of skin and erythema
vit d
-fat sol vitamin
-responsible for utilization of calcium and phosphorus
- vit d2 (ergocalciferol), plant vit d, through dietary
- vit d3 (cholecalciferol) produced by skin by UV irradiation
vit D2 containing foods
- fish liver oils, saltwater fish
- fortified foods: milk, bread, cereals
- animal livers: tuna, eggs, butter
vit D functions
- works with parathyroid hormone to regulate absorption and use of calcium and phosphorus
-for normal calcification of bone and teeth
vit D indications
- treatment of conditions related to long term deficiency (rickets, tetany, osteomalacia)
- prevention of osteoporosis
- treats osteodystrophy, hypocalcemia, hypoparathyroidism, pseudohypoparathyroidism, hypophosphatemia
vit D toxicity
- hypertension, dysrhythmias, weakness, fatigue, headache, drowsiness
- anorexia, dry mouth, metallic taste, nausea, vomiting, constipation
- decreased bone growth, bone pain, muscle pain
-polyuria, albuminuria, increased blood urea nitrogen
vit D toxicity can lead to _____ and ___ if untreated
impaired renal function and osteoporosis
vitamin E
fat soluble
- alpha, beta, gamma, delta tocopherol
- dietary sources: fruits, grains, fortified cereal, veg oil, wheat germ, nuts
- animal sources: eggs, chicken, meat, fish
vit E functions
- unknown
- antioxidant?
- no benefit from vit E supplementation
vit E indications
dietary supplement
antioxidant
treatment of deficiency ( in premature infants)
vit E adverse effects
GI and CNS
vit K 3 types
fat soluble
-phytonadione (K1), menaquinone (K2), menadione (K3)
- K2 synthesized by intestinal flora
dietary source of vit K1
- green leafy veggies, cheese, soybean oils
vit K functions
blood coagulation factors in the liver
vit K indications
- treats deficiency states (antibiotic therapy and newborn malabsorption)
- prophylactically to newborns
- reverse effects of warfarin
- pts become unresponsive to warfarin 1 week after vit K admin
vit B1 (thiamine)
water sol
food sources: enriched whole grain breads and cereals, liver, beans, yeast
deficiencies: beriberi, wernicke’s encephalopathy
Beriberi
- brain lesions
-polyneuropathy of peripheral nerves - serous effusions
- cardiac anatomical changes
- cerebral berberi: wernickes encephalopathy
vit b1 (thiamine) functions
-increase metabolism/pathways(kerbs)
- maintains PNS, cardio system, GI tract
vit B1 (thiamine) indications
-treats beriberi, peripheral neuritis, neuritis of pregnancy
- metabolic disorders
- malabsorption
- management of poor appetite, UC, chronic diarrhea, cerebellar syndrome or ataxia
- oral insect repellant?
vit B2 (riboflavin)
- water sol
- food sources: leafy greens, eggs, dairy, nuts, legumes, meats, liver, yeast, enriched whole grains
vit B2 causes of deficiency
- alcoholism
- intestinal malabsorption
- long standing infections
- liver disease
-malignancy - probenecid therapy
vit B2 functions
- converted into 2 coenzymes essential for tissue respiration
- required to activate vit B6
- tryptophan -> niacin
- maintains erythrocyte integrity