Fluids and electrolytes Flashcards
Total body water percentage: intracellular
67%
Total body water percentage: interstitial
25%
Total body water percentage: plasma volume
8%
How much of an adult human is water
60%
What is intravascular fluid
Fluid inside blood vessels
What is extravascular fluid
Fluid outside of the blood vessels like lymph or cerebrospinal fluid
What comprises of extravascular volume
Plasma, interstitial fluid
Interstitial fluid
fluid in space between cells, tissue and organs(outside the blood vessel)
What comprises of Extracellular volume
interstitial fluid and intracellular fluid
Value of the osmotic pressure
24 mm Hg
How do the plasma proteins effect the osmotic pressure
The proteins cause a gradient in the blood to pull water into the blood
Osmotic pressure AKA…
colloid oncotic pressure
What kind of pressure does Interstitial fluid exert and why
Exerts hydrostatic pressure. Which is pressure exert onto the blood vessel by the volume outside the blood vessel
Value of interstitial fluid
17 mm Hg
What are crystalloids
Solutions (without protein) containing fluids and electrolytes normally not found in the body. Carries no risk for viral transmission, anaphylaxis or alteration in coagulation profile
Use of Crytalloids
To treat dehydration and maintenance for..
- Fluid loss
- replacement of fluids
- manage fluid and electrolyte disturbance
- Promote urinary flow
Examples of crystalloids (6)
- Normal saline 0.9% isotonic or sodium chloride (0.45% hypotonic)
- 3.3% dextrose with 0.3% normal saline (isotonic)
- Hypertonic saline 3% sodium chloride
- Lactated ringers solution(Isotonic)
- Dextrose 5% in water (D5W)(Isotonic)
- D5W and 0.45% normal saline (hypertonic)
Indications of crystalloids
Acute liver failure
Acute nephrosis
Adult respiratory distress syndrome
Burns
Cardiopulmonary bypass
Hypoproteinemia
Hemodialysis
Deep vein thrombosis (reduction of risk)
Shock
Adverse effects of crystalloids
- May cause edema
- May dilute plasma proteins reducing the colloid (osmotic) pressure
- effects may be short lived and can cause alkalosis or acidosis
- contraindicated in hypervolemia
What are Colloids
Protein substance. Adding these increase colloid (osmotic) pressure increasing the movement of fluid into the blood vessels
Examples of of colloids
- Albumin 5% and 25% (from human donors)
- Dextran 40 or 70 (available in sodium chloride and 5% dextrose
- Hetastarch (synthetic)
Adverse effects of colloids
- Often safe but may cause altered coagulation
- Have no clotting factors or oxygen carrying capacity
- Dextran may cause anaphylaxis or kidney failure (rarely)
What is albumin
Generates approximately 70% of colloid oncotic pressure.
pasteurized solution made from pooled blood, plasma, serum or placentas obtained from healthy human donors
What are blood products
Is the only class that increases tissue oxygenation, increase plasma volume and are most expensive and least available fluid because they require human donors